SCHEMBL5404741

SCHEMBL5404741

CCC(=O)Oc1ccccc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.57
ATM Q13315 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ACHE P22303 1/20 0.56
ELANE P08246 1/20 0.47
PPARG P37231 1/20 0.45
BCHE P06276 1/20 0.45
ALOX15 P16050 1/20 0.45
KDM4E B2RXH2 3/20 0.44
CYP1A2 P05177 1/20 0.44
ESR1 P03372 1/20 0.44
HIF1A Q16665 1/20 0.44
LMNA P02545 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21635119 0.98 TDP1 (0.55) TDP1ATML3MBTL1ACHEELANE
SCHEMBL8435546 0.87 ALOX15 (0.55) L3MBTL1ACHEELANEALOX15KDM4E
SCHEMBL29941922 0.86 TDP1 (0.58) TDP1ATML3MBTL1PPARGBCHE
SCHEMBL644115 0.86 TDP1 (0.58) TDP1ATML3MBTL1PPARGBCHE
SCHEMBL241599 0.86 TDP1 (0.58) TDP1ATML3MBTL1PPARGBCHE
SCHEMBL3079343 0.85 TDP1 (0.54) TDP1ATML3MBTL1PPARGBCHE
SCHEMBL1750794 0.85 POLB (0.53) TDP1ATML3MBTL1ACHEALOX15
SCHEMBL27800887 0.84 TDP1 (0.61) TDP1ATML3MBTL1PPARGBCHE
SCHEMBL27460967 0.84 RXRA (0.49) TDP1ATML3MBTL1ACHEKDM4E
SCHEMBL15549298 0.83 SMN1; SMN2 (0.51) TDP1ATML3MBTL1ACHEELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106832000-A A kind of many peptidoliposomes that pattern conversion can occur in tumour cell lysosome 国家纳米科学中心 2017-06-13 CN claimed
CN-115959977-B Preparation method of 1, 1-tris (3, 5-dimethoxy methyl-4-hydroxyphenyl) ethane 陕西泰合利华工业有限公司 2024-06-11 CN disclosed
CN-117645540-A Preparation method of chlorophenoxycarboxylate 山东润博生物科技有限公司 2024-03-05 CN disclosed
CN-117089418-A Substrate treatment composition and substrate treatment method using same SK株式会社 2023-11-21 CN disclosed
CN-117025316-A Substrate treatment composition and substrate treatment method using same SK株式会社 2023-11-10 CN disclosed
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2023-05-25 US disclosed
CN-115959977-A Preparation method of 1, 1-tri (3, 5-dimethoxymethyl-4-hydroxyphenyl) ethane 陕西泰合利华工业有限公司 2023-04-14 CN disclosed
EP-3407414-B1 NON-AQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEMICAL LTD (KR) 2021-09-22 EP disclosed
WO-2020020097-A1 PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST BEIGENE, LTD. (KY) 2020-01-30 WO disclosed
EP-2940012-B1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL CO (JP) 2019-01-30 EP disclosed
EP-0684221-A1 Process for preparing carbonate esters NIPPON SHOKUBAI CO., LTD. (JP) 1995-11-29 EP disclosed
EP-0365340-B1 Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene HOECHST CELANESE CORP (US) 1995-05-03 EP disclosed
EP-0307752-B1 Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use HOECHST AG (DE) 1995-02-22 EP disclosed
CN-1093355-A The preparation method of phenylacetic acid derivatives CIBA GEIGY AG (CH) 1994-10-12 CN disclosed
US-5342727-A Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene in admixture with a photosensitizer to form a photosensitive composition HOECHST CELANESE CORP. (US) 1994-08-30 US disclosed
US-4922015-A Synthesis of peptide amides by means of a solid phase method using acid-labile anchoring groups HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
EP-0365340-A2 Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene HOECHST CELANESE CORPORATION (US) 1990-04-25 EP disclosed
EP-0307752-A2 Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 EP disclosed
US-4782177-A AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 1988-11-01 US disclosed
US-4230624-A CYCLIZATION, BASIC CATALYSTS AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) 1980-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 TDP1 1469/4885ATM 3289/4885L3MBTL1 4847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.