SCHEMBL5404946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6931712	0.86	TAAR1 (0.46)	TAAR1IDO1AGXTCLK4DAO
	SCHEMBL31749981	0.83	GPR52 (0.33)	GPR52IDO1
	SCHEMBL5400082	0.81	HSP90AB1 (0.41)	ADCY10IDO1DAOCNR1CNR2
	SCHEMBL7776064	0.81	HTR2B (0.46)	TAAR1GPR52IDO1DAOCDC7
	SCHEMBL31750237	0.81	HTR2B (0.46)	TAAR1GPR52IDO1DAOCDC7
	SCHEMBL3913251	0.81	ALDH1A1 (0.52)	CLK4
	SCHEMBL5591246	0.79	ADCY10 (0.45)	TAAR1ADCY10IDO1AGXTDAO
	SCHEMBL5479186	0.77	ALDH1A1 (0.46)	TAAR1ADCY10IDO1AGXTCLK4
	SCHEMBL5404827	0.77	PKM (0.38)	TAAR1DAOKDM4EKDRERBB2
	SCHEMBL29442786	0.75	ALDH1A1 (0.64)	TAAR1ADCY10IDO1AGXTDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.