Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30525924 | 0.96 | DRD2 (0.34) | DRD2SLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL4659081 | 0.82 | SLC6A4 (0.33) | DRD2SLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL138389 | 0.81 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30203878 | 0.81 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1044599 | 0.81 | HTR1A (0.32) | HTR7 | |
| Hydrochloric Acid SCHEMBL6903687 | 0.80 | SLC6A4 (0.32) | DRD2SLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL4659053 | 0.80 | DRD2 (0.32) | DRD2SLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL31126400 | 0.80 | SLC6A4 (0.32) | DRD2SLC6A4HTR7 | |
| Propane SCHEMBL8633046 | 0.79 | SLC6A4 (0.32) | DRD2SLC6A4 | |
| Ethane SCHEMBL8632408 | 0.79 | DRD2 (0.32) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415792-A1 | COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING SAME | Mitsui Chemicals, Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |