SCHEMBL5405657

SCHEMBL5405657

CCO[Si](OCC)(OCC)Oc1ccc(N)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.54
TSHR P16473 2/20 0.54
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 6/20 0.41
CYP3A4 P08684 3/20 0.41
MAPT P10636 5/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
TEAD4 Q15561 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
MITF O75030 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38
NLRP1 Q9C000 1/20 0.38
NOD2 Q9HC29 1/20 0.38
MAOA P21397 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9456863 0.89 NQO1 (0.43) TDP1TSHRALDH1A1SMN1; SMN2KMT2A
SCHEMBL9457168 0.83 NQO1 (0.39) TDP1ALDH1A1CYP3A4MAPTNPC1
SCHEMBL27499462 0.81 CA1 (0.48) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL5393983 0.81 ACHE (0.41) TDP1TSHRALDH1A1CYP3A4MAPT
SCHEMBL20653104 0.79 ALDH1A1 (0.55) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL5400910 0.79 CYP1A2 (0.39) TSHRALDH1A1CYP3A4MAPTNPC1
SCHEMBL5394760 0.79 LTA4H (0.48) TSHRMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL10627313 0.79 SMN1; SMN2 (0.39) TDP1ALDH1A1MAPTNPC1RAB9A
SCHEMBL766451 0.78 LTA4H (0.43) TSHRMAPK1ALDH1A1MAPTNPC1
SCHEMBL13861932 0.76 RAB9A (0.45) TDP1MAPK1ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110099974-B Composition for forming protective layer on substrate 日产化学株式会社 2022-02-25 CN disclosed
CN-111423813-B Composition for forming release layer and release layer 日产化学工业株式会社 2021-11-23 CN disclosed
CN-107406675-B Composition for forming release layer and release layer 日产化学工业株式会社 2020-11-06 CN disclosed
CN-111423813-A Composition for forming release layer and release layer 日产化学工业株式会社 2020-07-17 CN disclosed
US-7205085-B2 Composition having permitivity being radiation-sensitively changeable and method for forming permitivity pattern JSR CORPORATION (JP) 2007-04-17 US disclosed
US-7125647-B2 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2006-10-24 US disclosed
EP-1413924-A1 COMPOSITION HAVING PERMITIVITY BEING RADIATION-SENSITIVELY CHANGEABLE AND METHOD FOR FORMING PERMITIVITY PATTERN JSR Corporation (JP) 2004-04-28 EP disclosed
US-20040005506-A1 Composition having permitivity being radiation-sensitively changeable and method for forming permitivity pattern JSR CORPORATION (JP) 2004-01-08 US disclosed
EP-1375597-A1 RADIATION-SENSITIVE COMPOSITION CHANGING IN REFRACTIVE INDEX AND UTILIZATION THEREOF JSR Corporation (JP) 2004-01-02 EP disclosed
US-20030171468-A1 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2003-09-11 US disclosed
CN-1032477-C Composition for use as coating or facing of portland cement concrete or metal ROHM & HAAS (US) 1996-08-07 CN disclosed
CN-1052496-A Aqueous composition with good chemerosiveness resistent and resistance to sudden heating and thick film curing performance ROHM & HAAS (US) 1991-06-26 CN disclosed