Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1246238 | 0.98 | MAOB (0.58) | MAOBAOC3NOS1SLC7A5LTA4H | |
| SCHEMBL4027117 | 0.92 | MAOB (0.53) | MAOBAOC3NOS1SLC7A5 | |
| SCHEMBL1290562 | 0.90 | MAOB (0.57) | MAOBAOC3NOS1LTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL30020614 | 0.88 | MAOB (0.60) | MAOBAOC3NOS1LTA4HALDH1A1 | |
| SCHEMBL10458622 | 0.83 | MAOB (0.53) | MAOBAOC3NOS1LTA4HALDH1A1 | |
| SCHEMBL991452 | 0.82 | TAAR1 (0.56) | LTA4HTAAR1 | |
| SCHEMBL6266422 | 0.82 | MAOB (0.50) | MAOBAOC3NOS1LTA4HALDH1A1 | |
| SCHEMBL12409185 | 0.82 | CHRNB2 (0.54) | MAOBNOS1LTA4H | |
| SCHEMBL7252172 | 0.82 | NOS1 (0.51) | MAOBAOC3NOS1LTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL6258205 | 0.80 | TAAR1 (0.54) | LTA4HTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354590-A | Quinazolinone compound for antagonizing NOD1/2 receptor signal pathway | 宁波康柏睿格医药科技有限公司 | 2021-09-07 | — | — | CN | disclosed |
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-02-16 | — | — | US | disclosed |
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-02-16 | — | — | US | disclosed |
| WO-2015071657-A9 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2016-09-15 | — | — | WO | disclosed |
| WO-2015155306-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015071657-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2015-05-21 | — | — | WO | disclosed |
| US-7217696-B2 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | A & D BIOSCIENCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20050130908-A1 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | HOLICK MICHAEL F (US) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | NR3C1, NR3C2, NR5A1 | MAOB 4027/4885AOC3 2461/4885NOS1 3004/4885 |
| US-20050130908-A1 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | PYGB, GBA3, GAA | MAOB 29/4885AOC3 609/4885NOS1 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.