SCHEMBL540637

SCHEMBL540637

C=CCOCC=C.N#CC=CC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
HCAR2 Q8TDS4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL7974945 0.81 TSHR (0.47) MEN1KMT2AMAPTCACNA1BAPBA1
Maleic Acid SCHEMBL460391 0.81 TSHR (0.47) MEN1KMT2AMAPTCACNA1BAPBA1
Acrylic Acid SCHEMBL16468074 0.79 LMNA (0.50) MEN1KMT2AHCAR2
SCHEMBL7125436 0.79 ALDH1A1 (0.45) MAPTCACNA1BAPBA1
SCHEMBL996827 0.78
SCHEMBL10423 0.78
SCHEMBL8799194 0.78
SCHEMBL17912275 0.78 TSHR (0.47) MEN1KMT2AHCAR2
SCHEMBL11460249 0.76
Ammonia Solution, Strong SCHEMBL28313820 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP claimed
US-7932305-B2 Viscous α-cyanoacrylate compositions ETHICON, INC. (US) 2011-04-26 US claimed
US-20090326095-A1 Viscous alpha-Cyanoacrylate Compositions ETHICON, INC. 2009-12-31 US claimed
WO-2009158302-A2 VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2009-12-30 WO claimed
EP-1317294-B1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2005-03-16 EP claimed
EP-1317294-A1 ABSORBABLE ADHESIVE COMPOSITIONS Closure Medical Corporation (US) 2003-06-11 EP claimed
US-20020037310-A1 Absorbable adhesive compositions CLOSURE MEDICAL CORPORATION (US) 2002-03-28 US claimed
WO-2002009785-A1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2002-02-07 WO claimed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP disclosed
EP-2089308-B1 DISPENSER ETHICON INC (US) 2018-12-26 EP disclosed
US-9642658-B2 Device and method for delivery of therapeutic agents via internal implants ORTHOCLIP LLC (US) 2017-05-09 US disclosed
EP-2629687-A1 DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS VIA INTERNAL IMPLANTS Bioshape Solutions Inc. (US) 2013-08-28 EP disclosed
CN-101600643-B Dispenser CLOSURE MEDICAL CORP 2013-07-31 CN disclosed
US-8287202-B2 Method for dispensing a polymerizable monomer adhesive ETHICON, INC. (US) 2012-10-16 US disclosed
EP-1317294-A1 ABSORBABLE ADHESIVE COMPOSITIONS Closure Medical Corporation (US) 2003-06-11 EP disclosed
US-6547467-B2 Microapplicators, delivery systems and methods for adhesives and sealants CLOSURE MEDICAL CORPORATION 2003-04-15 US disclosed
WO-2003020358-A1 MICROAPPLICATORS, DELIVERY SYSTEMS AND METHODS FOR ADHESIVES AND SEALANTS CLOSURE MEDICAL CORPORATION (US) 2003-03-13 WO disclosed
US-20030044219-A1 MICROAPPLICATORS, DELIVERY SYSTEMS AND METHODS FOR ADHESIVES AND SEALANTS CLOSURE MEDICAL CORPORATION (US) 2003-03-06 US disclosed
US-20020037310-A1 Absorbable adhesive compositions CLOSURE MEDICAL CORPORATION (US) 2002-03-28 US disclosed
WO-2002009785-A1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037310-A1 Absorbable adhesive compositions EPCAM, CDH1, ICAM1 MEN1 1934/4885KMT2A 1270/4885MAPT 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.