Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364853 | 0.75 | ALDH1A1 (0.41) | RGS4POLBMEN1KMT2ATSHR | |
| SCHEMBL4364324 | 0.75 | ALDH1A1 (0.41) | RGS4POLBMEN1KMT2ATSHR | |
| SCHEMBL4499166 | 0.74 | ALDH1A1 (0.38) | RGS4POLBMEN1KMT2ATSHR | |
| SCHEMBL4363445 | 0.71 | PDE1C (0.39) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL644779 | 0.67 | KIF11 (0.54) | MEN1KMT2AGAAALDH1A1CYP3A4 | |
| SCHEMBL521671 | 0.66 | PTAFR (0.45) | POLBGAAALDH1A1CYP3A4 | |
| SCHEMBL644181 | 0.66 | KCNH2 (0.43) | MEN1KMT2AGAA | |
| SCHEMBL644102 | 0.65 | CYP19A1 (0.43) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10046467 | 0.63 | ALDH1A1 (0.42) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL124028 | 0.60 | POLB (0.46) | POLBMEN1KMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166595-B2 | Compounds, methods and compositions | CYTOKINETICS, INC. (US) | 2007-01-23 | — | — | US | disclosed |