Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | RGS4 | P49798 | 2/20 | 0.35 |
| ▸ | RGS8 | P57771 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364853 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLBRGS4 | |
| SCHEMBL4364324 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLBRGS4 | |
| SCHEMBL4363445 | 0.79 | PDE1C (0.39) | ALDH1A1MEN1KMT2AADORA3NPSR1 | |
| SCHEMBL5669991 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2APOLBNLRP3 | |
| SCHEMBL5406638 | 0.74 | RGS4 (0.38) | ALDH1A1MEN1KMT2APOLBRGS4 | |
| SCHEMBL4521642 | 0.70 | KIF11 (0.50) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL13963463 | 0.69 | HPGD (0.43) | MEN1KMT2AROCK2POLBHPGD | |
| SCHEMBL4363455 | 0.68 | KDM4E (0.38) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL4516228 | 0.68 | KIF11 (0.55) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL4524272 | 0.68 | KIF11 (0.55) | ALDH1A1MEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476743-B2 | Compounds, compositions, and methods | CYTOKINETICS, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-7476743-B2 | Compounds, compositions, and methods | CYTOKINETICS, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| EP-1558588-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060189671-A1 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED | 2006-08-24 | — | — | US | disclosed |
| EP-1558588-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004032840-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189671-A1 | Compounds, compositions, and methods | TK1, TK2, TYMP | ALDH1A1 2001/4885MEN1 1796/4885KMT2A 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.