Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150242 | 0.98 | MAOA (0.38) | MAOAMAOBMAPKAPK2ATMHSP90AA1 | |
| Zinc Ion SCHEMBL10796545 | 0.98 | MAOA (0.38) | MAOAMAOBMAPKAPK2ATMHSP90AA1 | |
| SCHEMBL5705630 | 0.89 | MAOA (0.41) | MAOAMAOBHSP90AA1HSP90AB1ACSL1 | |
| Potassium Ion SCHEMBL167049 | 0.87 | MAOA (0.42) | MAOAMAOBMAPKAPK2ACSL1GAA | |
| SCHEMBL152831 | 0.86 | MAOA (0.43) | MAOAMAOBMAPKAPK2ACSL1P2RX4 | |
| SCHEMBL11323633 | 0.85 | MAOA (0.42) | MAOAMAOBMAPKAPK2ACSL1 | |
| SCHEMBL9340083 | 0.85 | MAOA (0.42) | MAOAMAOBMAPKAPK2ACSL1 | |
| SCHEMBL16414620 | 0.85 | MAOA (0.42) | MAOAMAOBMAPKAPK2ACSL1 | |
| SCHEMBL672014 | 0.85 | MAOA (0.42) | MAOAMAOBMAPKAPK2ACSL1 | |
| SCHEMBL640834 | 0.85 | MAOA (0.42) | MAOAMAOBMAPKAPK2ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114270562-A | Electrochemical cells and assemblies comprising thiol-group containing materials | 赛昂能源有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110945688-A | Passivating agent for electrochemical cells | 赛昂能源有限公司 | 2020-03-31 | — | — | CN | disclosed |
| US-7255795-B2 | Process for selectively removing molybdenum from liquid mixtures containing it together with vanadium | ENI S.P.A. (IT) | 2007-08-14 | — | — | US | disclosed |
| US-20040262232-A1 | Process for selectively removing molybdenum from liquid mixtures containing it together with vanadium | ENITECNOLOGIE S.P. A. (IT) | 2004-12-30 | — | — | US | disclosed |