Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 10/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431781 | 0.75 | SIGMAR1 (0.66) | CHRM4CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL6190214 | 0.74 | GRIK1 (0.53) | SMN1; SMN2CYP2D6LMNAMAPK1 | |
| SCHEMBL5415283 | 0.74 | MTNR1A (0.51) | SIGMAR1CYP2D6HTR2A | |
| SCHEMBL5412330 | 0.72 | MTNR1A (0.50) | SIGMAR1CYP2D6HTR2A | |
| SCHEMBL5159643 | 0.72 | SIGMAR1 (0.62) | CHRM4CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL8346825 | 0.71 | KIF11 (0.60) | KIF11 | |
| SCHEMBL10949576 | 0.71 | MAPT (0.53) | SMN1; SMN2MAPK1 | |
| SCHEMBL10941524 | 0.71 | MAPT (0.53) | SMN1; SMN2MAPK1 | |
| SCHEMBL10942050 | 0.71 | MAPT (0.53) | SMN1; SMN2MAPK1 | |
| SCHEMBL12851375 | 0.71 | GPR84 (0.41) | CHRM3CHRM1HTR2ADRD3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |