Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | USP9X | Q93008 | 6/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951129 | 0.76 | LTA4H (0.49) | LTA4HKCNJ1KCNH2ALDH1A1CHRNA7 | |
| SCHEMBL18118210 | 0.74 | CA2 (0.54) | LTA4HCA12CA1CA2CA9 | |
| SCHEMBL8591966 | 0.74 | LTA4H (0.47) | LTA4HKCNJ1KCNH2CHRNA7CHRNA10 | |
| SCHEMBL5408419 | 0.74 | ALDH1A1 (0.48) | LTA4HALDH1A1KDM4EHPGDSEDNRB | |
| SCHEMBL722557 | 0.73 | LTA4H (0.64) | LTA4HKCNJ1KCNH2CHRNA7CHRNA10 | |
| SCHEMBL7575704 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL28257875 | 0.71 | LTA4H (0.62) | LTA4HKCNJ1KCNH2CHRNA7CHRNA10 | |
| SCHEMBL28362996 | 0.71 | LTA4H (0.62) | LTA4HKCNJ1KCNH2CHRNA7CHRNA10 | |
| SCHEMBL28320605 | 0.71 | LTA4H (0.62) | LTA4HKCNJ1KCNH2CHRNA7CHRNA10 | |
| SCHEMBL27548591 | 0.71 | MMP2 (0.55) | PNMTALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |