Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411987 | 0.77 | ALDH1A1 (0.35) | KCNH2SMN1; SMN2PKMALDH1A1MAPT | |
| SCHEMBL5409732 | 0.73 | GRIA1 (0.35) | KCNH2SMN1; SMN2PKMALDH1A1MAPT | |
| SCHEMBL5409719 | 0.71 | SMN1; SMN2 (0.41) | KCNH2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5383506 | 0.69 | PKM (0.44) | KCNH2SMN1; SMN2PKMALDH1A1MAPT | |
| SCHEMBL1074567 | 0.68 | SMN1; SMN2 (0.37) | KCNH2SMN1; SMN2PKMALDH1A1MAPT | |
| SCHEMBL9233404 | 0.65 | — | — | |
| SCHEMBL5404958 | 0.65 | MAPT (0.36) | SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31616896 | 0.64 | SMN1; SMN2 (0.38) | SMN1; SMN2PKMALDH1A1MAPT | |
| SCHEMBL6758738 | 0.64 | PKM (0.33) | SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL6442557 | 0.64 | SMN1; SMN2 (0.43) | SMN1; SMN2PKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300469-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-11-27 | — | — | US | disclosed |
| US-20040143909-A1 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-07-29 | — | — | US | disclosed |
| EP-1362036-A1 | DIAMINOPYRAZOLE COMPOUNDS AND THE USE THEREOF IN THE OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002070489-A1 | DIAMINOPYRAZOLE COMPOUNDS AND THE USE THEREOF IN THE OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143909-A1 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | KRT18, TUBB3, AOC1 | KCNH2 237/4885SMN1; SMN2 4692/4885PKM 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.