Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243134 | 0.83 | MAPT (0.35) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL10844132 | 0.83 | MAOA (0.33) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL7758367 | 0.79 | GAA (0.31) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL9282892 | 0.78 | TTR (0.37) | GAAMAPTTDP1KDM4EALDH1A1 | |
| SCHEMBL242353 | 0.78 | LMNA (0.36) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL7597926 | 0.78 | ATM (0.39) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL30666645 | 0.78 | LMNA (0.38) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL531432 | 0.78 | LMNA (0.47) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL30667146 | 0.78 | LMNA (0.38) | GAAMAPTTDP1KDM4EMEN1 | |
| SCHEMBL9101570 | 0.78 | LMNA (0.38) | GAAMAPTTDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232825-B2 | Phenylaminopyrimidine derivatives and methods of use | CHEN GUOQING P | 2007-06-19 | — | — | US | disclosed |
| US-20040224967-A1 | Phenylaminopyrimidine derivatives and methods of use | CHEN GUOQING P | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224967-A1 | Phenylaminopyrimidine derivatives and methods of use | ABL1, ABL2, LCK | GAA 687/4885MAPT 1427/4885TDP1 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.