Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5412418 | 0.79 | GAA (0.36) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL22769623 | 0.79 | ALDH1A1 (0.33) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL9243134 | 0.78 | MAPT (0.35) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL10844132 | 0.78 | MAOA (0.33) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL28928745 | 0.75 | GAA (0.33) | GAAKDM4EMEN1ALDH1A1POLB | |
| Water SCHEMBL11279317 | 0.75 | ALDH1A1 (0.36) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL7597926 | 0.73 | ATM (0.39) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL9101570 | 0.73 | LMNA (0.38) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL531432 | 0.73 | LMNA (0.47) | GAAKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL30666645 | 0.73 | LMNA (0.38) | GAAKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084123-A1 | NOVEL ASYMMETRICALLY SUBSTITUTED XANTHINE DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS WITH AN ADENOSINE-ANTAGONISTIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999054331-A1 | NOVEL ASYMMETRICALLY SUBSTITUTED XANTHINE DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS WITH AN ADENOSINE-ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |