Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.68 |
| ▸ | MMP13 | P45452 | 17/20 | 0.57 |
| ▸ | MMP14 | P50281 | 7/20 | 0.57 |
| ▸ | MMP9 | P14780 | 6/20 | 0.57 |
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | MMP3 | P08254 | 5/20 | 0.57 |
| ▸ | MMP8 | P22894 | 5/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP10 | P09238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26434 | 0.90 | MMP1 (0.83) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL6813262 | 0.89 | MMP1 (0.67) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL13899017 | 0.83 | MMP1 (0.52) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL3987272 | 0.82 | MMP1 (0.68) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL6873149 | 0.82 | MMP1 (0.70) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL13556928 | 0.81 | MMP1 (0.81) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL7347709 | 0.81 | MMP1 (0.56) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL7352297 | 0.81 | MMP1 (0.68) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL25130 | 0.81 | MMP1 (0.96) | MMP1MMP13MMP14MMP9MMP2 | |
| SCHEMBL26986 | 0.81 | MMP1 (1.00) | MMP1MMP13MMP14MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288251-B2 | Antibodies to CD40 | ABGENIX, INC. (US) | 2007-10-30 | — | — | US | disclosed |