Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.56 |
| ▸ | MMP13 | P45452 | 13/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813262 | 0.93 | MMP1 (0.67) | MMP1MMP13SMN1; SMN2MMP2MMP9 | |
| SCHEMBL7352211 | 0.91 | MMP1 (0.45) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7352297 | 0.88 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6870820 | 0.85 | MMP1 (0.58) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL3921083 | 0.85 | MMP1 (0.55) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6691684 | 0.84 | MMP1 (0.79) | MMP1MMP13SMN1; SMN2MMP2MMP9 | |
| SCHEMBL6813091 | 0.84 | MMP1 (0.76) | MMP1MMP13SMN1; SMN2MMP2MMP9 | |
| SCHEMBL6813516 | 0.84 | MMP1 (0.54) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL4940266 | 0.83 | MMP1 (0.67) | MMP1MMP13SMN1; SMN2MMP9MMP8 | |
| SCHEMBL6866226 | 0.83 | MMP1 (0.55) | MMP1MMP13SMN1; SMN2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895988-B1 | Arylsulfonylamino hydroxamic acid derivatives | PFIZER PROD INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6107337-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS | PFIZER INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0895988-A1 | Arylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |