Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.35 |
| ▸ | HTR2C | P28335 | 12/20 | 0.35 |
| ▸ | HTR2B | P41595 | 12/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5424420 | 0.97 | HTR2A (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL3917737 | 0.78 | — | — | |
| SCHEMBL8874009 | 0.74 | CCR5 (0.32) | CCR5 | |
| SCHEMBL7492337 | 0.73 | CCR5 (0.31) | CCR5 | |
| SCHEMBL30249644 | 0.71 | — | — | |
| SCHEMBL24535981 | 0.67 | ALDH1A1 (0.37) | HTR2AHTR2CHTR2BCCR5 | |
| SCHEMBL1748458 | 0.67 | HTR2A (0.32) | HTR2AHTR2CHTR2BCCR5 | |
| SCHEMBL6212284 | 0.67 | HTR2A (0.32) | HTR2AHTR2CHTR2BCCR5 | |
| SCHEMBL11283022 | 0.67 | ALDH1A1 (0.37) | — | |
| SCHEMBL30600144 | 0.67 | ALDH1A1 (0.37) | HTR2AHTR2CHTR2BCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-09-20 | — | — | US | claimed |
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | ADRA1D, ADRA1A, ADRB1 | HTR2A 203/4885HTR2C 222/4885HTR2B 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.