Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393668 | 0.88 | L3MBTL1 (0.41) | AOC3SLC6A2HTR2APOLB | |
| SCHEMBL30626020 | 0.82 | ALDH1A1 (0.38) | AOC3ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL5410448 | 0.80 | GFER (0.48) | ALDH1A1TAAR1CYP3A4TDP1CYP2A6 | |
| SCHEMBL20610515 | 0.80 | GPR52 (0.41) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL1195484 | 0.80 | GPR52 (0.41) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL27870822 | 0.79 | MEN1 (0.42) | AOC3ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL1072575 | 0.78 | SLC6A2 (0.52) | ALDH1A1TAAR1ATMSLC6A2CYP3A4 | |
| SCHEMBL11224549 | 0.78 | TDP1 (0.50) | AOC3ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL20557193 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5729581 | 0.76 | CYP2A6 (0.46) | ALDH1A1HSD17B10CYP2A6SMN1; SMN2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250523-B2 | Imido-tethered carbenes of molybdenum for ring-opening metathesis polymerization and ring-closing metathesis | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-07-31 | — | — | US | disclosed |
| US-7250523-B2 | Imido-tethered carbenes of molybdenum for ring-opening metathesis polymerization and ring-closing metathesis | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-07-31 | — | — | US | disclosed |
| WO-2005086622-A2 | IMIDO-TETHERED CARBENES OF MOLYBDENUM FOR RING-OPENING METATHESIS POLYMERISATION AND RING-CLOSING METATHESIS | MICHIGAN STATE UNIVERSITY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050101475-A1 | Imido-tethered carbenes of molybdenum for ring-opening metathesis polymerization and ring-closing metathesis | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-05-12 | — | — | US | disclosed |
| US-5964919-A | STABILIZING THE ACTIVE ZINC BY SUSPENDING IN A CONTAINER WITH AN SOLVENT SELECT FROM ETHER, HYDROCARBON, AROMATIC HYDROCARABON OR APROTIC SOLVENT UNDER INERT GAS, SEALING THE CONTAINER | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1999-10-12 | — | — | US | disclosed |
| US-5756653-A | REACTING A REDUCING AGENT ON A ZINC SALT | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1998-05-26 | — | — | US | disclosed |
| US-5358546-A | Reacting a zinc compound with a reducting agent | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1993015086-A1 | HIGHLY REACTIVE FORMS OF ZINC AND REAGENTS THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101475-A1 | Imido-tethered carbenes of molybdenum for ring-opening metathesis polymerization and ring-closing metathesis | NOXO1, PPOX, CBR1 | AOC3 57/4885ALDH1A1 4187/4885HPGD 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.