SCHEMBL542103

SCHEMBL542103

O=C(CCC(=O)OCCC(CO)(CO)CO)OCCC(CO)(CO)CO

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.43
ADRA1A P35348 1/20 0.43
MAPT P10636 1/20 0.41
BLM P54132 1/20 0.41
DGKA P23743 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
HTR2C P28335 1/20 0.32
APP P05067 1/20 0.32
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7027046 0.91 DGKA (0.47) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL28022258 0.89 DGKA (0.50) ADRA2AADRA1AMAPTDGKAALDH1A1
SCHEMBL7606323 0.87 ADRA2A (0.33) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL11357278 0.87 DGKA (0.44) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL4682825 0.86 ALDH1A1 (0.34) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL4304487 0.86 ADRA2A (0.32) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL28426461 0.86 DGKA (0.42) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL6398265 0.84 DGKA (0.55) MAPTDGKAALDH1A1CYP3A4TDP1
Di(Hydroxyethyl)Ether SCHEMBL28597263 0.84 LMNA (0.33) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL11652774 0.82 DNM1 (0.45) ADRA2AADRA1AMAPTBLMDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115873201-A Waterborne polyurethane resin and preparation method and application thereof 上海华峰新材料研发科技有限公司 2023-03-31 CN disclosed
EP-1309755-B2 PROCESS FOR SIZING PAPER KEMIRA OYJ (FI) 2015-11-18 EP disclosed
US-8425723-B2 Process for improving optical properties of paper AKZO NOBEL N.V. (NL) 2013-04-23 US disclosed
EP-1309756-B1 PROCESS FOR SIZING PAPER AKZO NOBEL NV (NL) 2012-06-13 EP disclosed
EP-1309755-B1 PROCESS FOR SIZING PAPER AKZO NOBEL NV (NL) 2012-02-29 EP disclosed
EP-1456468-B1 AQUEOUS SILICA-CONTAINING COMPOSITION AND PROCESS FOR PRODUCTION OF PAPER AKZO NOBEL NV (NL) 2012-02-08 EP disclosed
CN-101056595-B Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2012-02-08 CN disclosed
US-20100132901-A1 PROCESS FOR IMPROVING OPTICAL PROPERTIES OF PAPER AKZO NOBEL N.V. (NL) 2010-06-03 US disclosed
EP-2132381-A1 PROCESS FOR IMPROVING OPTICAL PROPERTIES OF PAPER Akzo Nobel N.V. (NL) 2009-12-16 EP disclosed
US-7488402-B2 Process for production of paper AKZO NOBEL N.V. (NL) 2009-02-10 US disclosed
EP-1309755-A1 PROCESS FOR SIZING PAPER Akzo Nobel N.V. (NL) 2003-05-14 EP disclosed
EP-1090054-B1 IONIC POLYURETHANES AKZO NOBEL NV (NL) 2002-08-14 EP disclosed
US-20020100567-A1 Process for sizinc paper KEMIRA OYJ (FI) 2002-08-01 US disclosed
US-20020096290-A1 Process for sizing paper KEMIRA OYJ (FI) 2002-07-25 US disclosed
US-20020096289-A1 Process for the production of paper KEMIRA OYJ (FI) 2002-07-25 US disclosed
WO-2002012622-A1 PROCESS FOR SIZING PAPER AKZO NOBEL N.V. (NL) 2002-02-14 WO disclosed
WO-2002012623-A1 PROCESS FOR SIZING PAPER AKZO NOBEL N.V. (NL) 2002-02-14 WO disclosed
WO-2002012626-A1 A PROCESS FOR THE PRODUCTION OF PAPER AKZO NOBEL N.V. (NL) 2002-02-14 WO disclosed
EP-1090054-A1 IONIC POLYURETHANES AKZO NOBEL N.V. (NL) 2001-04-11 EP disclosed
WO-1999067310-A1 IONIC POLYURETHANES AKZO NOBEL N.V. (NL) 1999-12-29 WO disclosed