SCHEMBL5423474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5434700	0.85	RARB (0.47)	GRM5ALDH1A1NPC1HPGDMAPT
	SCHEMBL12844304	0.76	GRM5 (0.52)	MLYCDGRM5ALDH1A1L3MBTL1NPC1
	SCHEMBL29133579	0.75	GRM5 (0.51)	MLYCDGRM5ALDH1A1L3MBTL1NPC1
	SCHEMBL5437061	0.73	GRM5 (0.47)	MLYCDGRM5ALDH1A1L3MBTL1NPC1
	SCHEMBL2961669	0.73	GRM5 (0.49)	MLYCDGRM5ALDH1A1L3MBTL1NPC1
	SCHEMBL5909282	0.71	GAA (0.47)	GRM5HPGDLMNAHRH3
	SCHEMBL12844312	0.70	ALDH1A1 (0.44)	MLYCDALDH1A1L3MBTL1NPC1HPGD
	SCHEMBL11332811	0.70	HPGD (0.43)	MLYCDGRM5ALDH1A1L3MBTL1HPGD
	SCHEMBL5430899	0.69	HCAR3 (0.54)	MLYCDGRM5ALDH1A1L3MBTL1NPC1
	Hydrochloric Acid SCHEMBL11329758	0.69	HPGD (0.43)	MLYCDGRM5ALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.