Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PNMT | P11086 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.39 |
| ▸ | HTR3B | O95264 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248085 | 0.98 | TSHR (0.53) | TSHRRECQLPNMTCHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL6442683 | 0.80 | ALDH1A1 (0.52) | TSHRCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL2349990 | 0.78 | DNM1 (0.50) | TSHRCHRM3TAAR1KMT2ALMNA | |
| SCHEMBL544199 | 0.77 | TAAR1 (0.51) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL545138 | 0.76 | MAPK1 (0.40) | TSHRCHRM2CHRM1CHRM3TAAR1 | |
| Hydrochloric Acid SCHEMBL22265012 | 0.76 | KDM4E (0.56) | PNMTCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL2427261 | 0.74 | PNMT (0.69) | TSHRRECQLPNMTCHRM2TAAR1 | |
| SCHEMBL31658958 | 0.74 | CHRM2 (0.54) | TSHRRECQLPNMTCHRM2CHRM1 | |
| SCHEMBL544056 | 0.73 | CYP4F2 (0.51) | RAB9AKMT2A | |
| SCHEMBL16196065 | 0.72 | DNM1 (0.66) | CHRM2CHRM1CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113289497-A | Hydrophilic modification method of ceramic membrane | 井冈山大学 | 2021-08-24 | — | — | CN | claimed |
| CN-103030806-A | High-solid content polyamide polyamine epichlorohydrin wet strength agent, as well as preparation and application thereof | UNIV SOUTH CHINA TECH | 2013-04-10 | — | — | CN | claimed |
| CN-103012807-A | Preparation method and application of modified humic acid quaternary ammonium salt | UNIV GUIZHOU | 2013-04-03 | — | — | CN | claimed |
| CN-1989219-B | water-based drilling fluid | HERCULES INC | 2012-04-25 | — | — | CN | claimed |
| CN-101177461-B | Preparation of quaternary ammonium N-carboxyetbyl chitosan | YANCHENG INST TECHNOLOGY | 2010-06-09 | — | — | CN | claimed |
| CN-101508650-A | Method for preparing 3-rosin amine-2-hydroxypropyl dimethyl benzyl ammonium chloride | YANCHENG INST TECHNOLOGY (CN) | 2009-08-19 | — | — | CN | claimed |
| CN-101508651-A | Method for preparing 3-dehydroabietylamine-2-hydroxypropyl dimethyl benzyl ammonium chloride | YANCHENG INST TECHNOLOGY (CN) | 2009-08-19 | — | — | CN | claimed |
| US-7384892-B2 | Water-based drilling fluids | HERCULES INCORPORATED (US) | 2008-06-10 | — | — | US | claimed |
| CN-101177461-A | Preparation of quaternary ammonium N-carboxyetbyl chitosan | YANCHENG INST TECHNOLOGY (CN) | 2008-05-14 | — | — | CN | claimed |
| CN-1989219-A | Water-based drilling fluids | HERCULES INC (US) | 2007-06-27 | — | — | CN | claimed |
| EP-1769046-A1 | WATER-BASED DRILLING FLUIDS | Hercules Incorporated (US) | 2007-04-04 | — | — | EP | claimed |
| WO-2006014717-A1 | WATER-BASED DRILLING FLUIDS | HERCULES INCORPORATED (US) | 2006-02-09 | — | — | WO | claimed |
| US-20060019834-A1 | Water-based drilling fluids | HERCULES LLC | 2006-01-26 | — | — | US | claimed |
| EP-0580030-B1 | Thermoplastic resin film with excellent offset printability and offset prints thereof | OJI YUKA GOSEISHI KK (JP) | 1995-12-27 | — | — | EP | claimed |
| US-5397637-A | Synthetic paper coated with acrylic copolymer modified to contain quaternary ammonium salt | OJI YUKA GOSEISHI CO., LTD. (JP) | 1995-03-14 | — | — | US | claimed |
| EP-0580030-A1 | Thermoplastic resin film with excellent offset printability and offset prints thereof | OJI YUKA GOSEISHI CO., LTD. (JP) | 1994-01-26 | — | — | EP | claimed |
| CN-119661742-A | Waterproof locking agent and preparation method and application thereof | 中海石油(中国)有限公司上海分公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-112482054-B | Processing method for dyeing by using dyeing residual liquid of reactive dye | 浙江灏宇科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-5397637-A | Synthetic paper coated with acrylic copolymer modified to contain quaternary ammonium salt | OJI YUKA GOSEISHI CO., LTD. (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0580030-A1 | Thermoplastic resin film with excellent offset printability and offset prints thereof | OJI YUKA GOSEISHI CO., LTD. (JP) | 1994-01-26 | — | — | EP | disclosed |