Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CD4 | P01730 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428165 | 0.92 | TP53 (0.47) | ALDH1A1LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL5424357 | 0.91 | CD4 (0.42) | ALDH1A1LMNAKDM4EPOLBEBP | |
| SCHEMBL5424711 | 0.89 | ALDH1A1 (0.46) | ALDH1A1LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL5428134 | 0.89 | ALDH1A1 (0.46) | ALDH1A1LMNAL3MBTL1THRBMEN1 | |
| SCHEMBL5430244 | 0.88 | SMN1; SMN2 (0.52) | ALDH1A1LMNAL3MBTL1KDM4EEBP | |
| SCHEMBL5424899 | 0.88 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EPOLBEBP | |
| SCHEMBL5439713 | 0.88 | LMNA (0.48) | ALDH1A1LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL5814802 | 0.86 | LMNA (0.39) | ALDH1A1LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL5426157 | 0.85 | HTT (0.46) | ALDH1A1LMNAL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5427465 | 0.85 | LMNA (0.47) | ALDH1A1LMNAKDM4EPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032482-A1 | Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2007-02-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032482-A1 | Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments | HTR6, HTR5A, P2RX6 | ALDH1A1 1597/4885LMNA 3123/4885L3MBTL1 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.