Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CD4 | P01730 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781640 | 0.92 | ALDH1A1 (0.35) | LMNAALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL5782163 | 0.92 | NPSR1 (0.37) | LMNAALDH1A1L3MBTL1MAPTHTT | |
| SCHEMBL5782809 | 0.91 | PKM (0.40) | LMNAALDH1A1MAPTMEN1HTT | |
| SCHEMBL5781876 | 0.91 | LMNA (0.40) | LMNAALDH1A1MAPTMEN1HTT | |
| SCHEMBL5785236 | 0.90 | PKM (0.44) | LMNAALDH1A1MAPTMEN1HTT | |
| SCHEMBL5784419 | 0.87 | MAPT (0.41) | LMNAALDH1A1MAPTMEN1HTT | |
| SCHEMBL5426422 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1L3MBTL1CD4MAPT | |
| SCHEMBL5782517 | 0.86 | HTR6 (0.41) | LMNAALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL5784257 | 0.85 | SMN1; SMN2 (0.42) | LMNAALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL5781747 | 0.84 | CHRM1 (0.36) | LMNAALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | claimed |