Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOCK5 | Q9H7D0 | 2/20 | 0.55 |
| ▸ | METAP2 | P50579 | 13/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429876 | 0.94 | DOCK5 (0.49) | DOCK5METAP2LIPE | |
| SCHEMBL5427827 | 0.92 | DOCK5 (0.52) | DOCK5METAP2 | |
| SCHEMBL5431938 | 0.89 | DOCK5 (0.51) | DOCK5METAP2KMT2ALIPE | |
| SCHEMBL5423572 | 0.88 | L3MBTL1 (0.42) | DOCK5METAP2LIPE | |
| SCHEMBL5426342 | 0.81 | HPGD (0.51) | DOCK5METAP2KMT2A | |
| SCHEMBL5429821 | 0.77 | ALDH1A1 (0.53) | METAP2KMT2ALIPE | |
| SCHEMBL5431833 | 0.75 | HCRTR2 (0.47) | DOCK5KMT2A | |
| SCHEMBL5437244 | 0.75 | LIPE (0.46) | DOCK5LIPE | |
| SCHEMBL5422192 | 0.73 | ALDH1A1 (0.47) | DOCK5KMT2ALIPE | |
| SCHEMBL5423716 | 0.73 | NPC1 (0.46) | DOCK5METAP2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275990-A1 | Heterocyclic Spiro Compound | ONO PHARMACEUTICAL CO., LTD. | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275990-A1 | Heterocyclic Spiro Compound | NR3C2, CBR1, CBR3 | DOCK5 2992/4885METAP2 4271/4885KMT2A 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.