Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429985 | 0.85 | HTR6 (0.41) | LMNAL3MBTL1EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3148785 | 0.83 | HTR6 (0.59) | LMNAL3MBTL1EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5426157 | 0.78 | HTT (0.46) | LMNAL3MBTL1EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5428107 | 0.78 | HTR6 (0.47) | L3MBTL1ALDH1A1CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL5431697 | 0.78 | ALDH1A1 (0.51) | LMNAL3MBTL1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5436208 | 0.78 | MCOLN3 (0.51) | LMNAL3MBTL1EPHX2ALDH1A1MEN1 | |
| SCHEMBL5428694 | 0.77 | VCAM1 (0.53) | LMNAL3MBTL1ALDH1A1MAPTPIK3CA | |
| SCHEMBL5436127 | 0.77 | LMNA (0.50) | LMNAL3MBTL1EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5432653 | 0.77 | TSHR (0.54) | LMNAL3MBTL1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5423035 | 0.77 | ABL1 (0.45) | LMNAL3MBTL1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032482-A1 | Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2007-02-08 | — | — | US | claimed |
| US-20070032482-A1 | Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032482-A1 | Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments | HTR6, HTR5A, P2RX6 | LMNA 3123/4885L3MBTL1 4880/4885EPHX2 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.