Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104935 | 0.78 | ATAD2 (0.47) | ATAD2 | |
| SCHEMBL22762949 | 0.74 | ALDH1A1 (0.47) | ATAD2KDM4EHSD17B10 | |
| SCHEMBL161148 | 0.73 | ATAD2 (0.54) | ATAD2MAPT | |
| SCHEMBL3699779 | 0.72 | DPYD (0.43) | ATAD2MAPT | |
| SCHEMBL28991875 | 0.71 | GAA (0.46) | MAPT | |
| SCHEMBL30677850 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL4353311 | 0.71 | DPYD (0.50) | ATAD2MAPT | |
| SCHEMBL5800398 | 0.71 | — | — | |
| SCHEMBL11149023 | 0.70 | ATAD2 (0.39) | ATAD2 | |
| SCHEMBL31236144 | 0.70 | DPYD (0.45) | ATAD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447454-B2 | Method of purifying RNA binding protein-RNA complexes | THE ROCKEFELLER UNIVERSITY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140378316-A1 | METHOD OF PURIFYING RNA BINDING PROTEIN-RNA COMPLEXES | THE ROCKEFELLER UNIVERSITY (US) | 2014-12-25 | — | — | US | disclosed |
| US-7268218-B2 | Cardiovascular system associated protein kinase 3 (CSAPK-3) antibodies | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| WO-2005041884-A2 | POLYMER-BASED MICROSTRUCTURES | ENGINEERED RELEASE SYSTEMS, INC (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20050027108-A1 | Novel protein kinase molecules and uses therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-02-03 | — | — | US | disclosed |
| WO-2002053728-A9 | GENE DISRUPTION METHODOLOGIES FOR DRUG TARGET DISCOVERY | ELITRA PHARMACEUTICALS INC (US) | 2003-05-30 | — | — | WO | disclosed |
| WO-2002080968-A1 | GLYCOPROTEIN VI AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001044476-A2 | MOSS GENES FROM PHYSCOMITRELLA PATENS ENCODING PROTEINS INVOLVED IN THE SYNTHESIS OF CARBOHYDRATES | BASF PLANT SCIENCE GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |