SCHEMBL542787

SCHEMBL542787

O=C(O)c1cc(Cl)c(CO)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 3/20 0.45
TP53 P04637 1/20 0.45
CASP1 P29466 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78183 0.85 ALDH1A1 (0.44) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL19116226 0.82 KEAP1 (0.46) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL15543742 0.82 KEAP1 (0.42) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL9984008 0.82 TSHR (0.42) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL68449 0.82 ALDH1A1 (0.61) ALDH1A1TSHRTP53CASP1SMN1; SMN2
Hydrochloric Acid SCHEMBL5080692 0.79 ALDH1A1 (0.58) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL28534088 0.79 ALDH1A1 (0.58) ALDH1A1TSHRTP53CASP1SMN1; SMN2
Hydrochloric Acid SCHEMBL944411 0.79 ALDH1A1 (0.58) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL522652 0.79 CBFB (0.36) ALDH1A1TSHRCASP1HPGDHSD17B10
SCHEMBL2471781 0.79 NPSR1 (0.46) ALDH1A1TSHRTP53CASP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3676273-B1 ZIRCONIUM TEREPHTHALATE-BASED METAL ORGANIC FRAMEWORK WITH OPEN METAL SITES UNIV CALIFORNIA (US) 2023-12-13 EP disclosed
EP-2415742-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed