Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182347 | 0.89 | MTNR1A (0.48) | AOC3L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL17798625 | 0.84 | KMT2A (0.41) | KDM4E | |
| SCHEMBL3663083 | 0.83 | KMT2A (0.56) | GLS | |
| SCHEMBL27586522 | 0.82 | MTNR1A (0.52) | AOC3L3MBTL1MTNR1AMTNR1BTDP1 | |
| SCHEMBL3443103 | 0.82 | AOC3 (0.67) | AOC3L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL28577126 | 0.81 | KDM4E (0.60) | AOC3L3MBTL1MTNR1AMTNR1BTDP1 | |
| SCHEMBL30932899 | 0.80 | L3MBTL1 (0.55) | AOC3L3MBTL1MTNR1AMTNR1BTDP1 | |
| Hydrochloric Acid SCHEMBL5422383 | 0.79 | ROCK2 (0.54) | AOC3L3MBTL1MTNR1AMTNR1BGLS | |
| SCHEMBL31724365 | 0.77 | L3MBTL1 (0.47) | AOC3L3MBTL1MTNR1AMTNR1BTDP1 | |
| SCHEMBL23216480 | 0.77 | MTNR1A (0.52) | AOC3L3MBTL1MTNR1AMTNR1BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191328-A1 | Isoquinoline compounds | LES LABORATOIRES SERVIER (FR) | 2007-08-16 | — | — | US | disclosed |
| US-7214689-B2 | Isoquinoline compounds | LES LABORATOIRES SERVIER (FR) | 2007-05-08 | — | — | US | disclosed |
| US-20040204449-A1 | New isoquinoline compounds | LES LABORATOIRES SERVIER (FR) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204449-A1 | New isoquinoline compounds | MTNR1A, MTNR1B, HCRTR1 | AOC3 1219/4885L3MBTL1 3444/4885CHRM2 471/4885 |
| US-20070191328-A1 | Isoquinoline compounds | MTNR1A, MTNR1B, NR1D1 | AOC3 1590/4885L3MBTL1 4067/4885CHRM2 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.