SCHEMBL543352

SCHEMBL543352

COC(=O)c1cccc(N)c1C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.69
HSD17B10 Q99714 4/20 0.69
CFTR P13569 1/20 0.69
KDM4E B2RXH2 6/20 0.50
TSHR P16473 3/20 0.50
LMNA P02545 3/20 0.50
GAA P10253 5/20 0.49
MAPT P10636 3/20 0.49
HPGD P15428 3/20 0.49
GLA P06280 2/20 0.49
ATM Q13315 2/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
CYP3A4 P08684 1/20 0.48
PIK3CA P42336 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31303445 1.00 ALDH1A1 (0.69) ALDH1A1HSD17B10CFTRKDM4ETSHR
Hydrochloric Acid SCHEMBL6980967 0.98 ALDH1A1 (0.67) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL3511612 0.86 LMNA (0.59) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL1200865 0.85 ALDH1A1 (0.49) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL28165708 0.83 HSD17B10 (0.47) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL136404 0.82 ALDH1A1 (0.55) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL505249 0.82 ALDH1A1 (0.71) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL31589985 0.82 ALDH1A1 (0.71) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL1707753 0.82 ALDH1A1 (0.60) ALDH1A1HSD17B10CFTRKDM4ELMNA
Methyl Anthranilate SCHEMBL901249 0.82 ALDH1A1 (1.00) ALDH1A1HSD17B10CFTRKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107337667-B Preparation process of lenalidomide for treating multiple myeloma 湖南慧泽生物医药科技有限公司 2020-10-09 CN claimed
CN-109293584-A Target the other structure modulating compound SPAM of small molecule and its preparation method and application of neuropeptide receptor PAC1-R 暨南大学 2019-02-01 CN claimed
CN-106522885-A Wax removing method for oil well in oil extraction process 崔虹雯 2017-03-22 CN claimed
CN-105861967-A Light high-strength composite metal material and preparation method thereof 苏州洪河金属制品有限公司 2016-08-17 CN claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
EP-4676475-A1 HIV-1P ROTEASE INHIBITORS AND USES THEREOF Purdue Research Foundation (US) 2026-01-14 EP disclosed
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof BASF AS (NO) 2025-11-18 US disclosed
WO-2025137158-A1 DERIVATIVES OF ([1,2,4]TRIAZOLO[5,1-A]ISOQUINOLINE-5-CARBONYL)GLYCINATE AS PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE AKEBIA THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
US-20250179043-A1 PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF FMC CORP (US) 2025-06-05 US disclosed
US-20250163010-A1 PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF FMC CORP (US) 2025-05-22 US disclosed
US-20250154124-A1 PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF FMC CORP (US) 2025-05-15 US disclosed
EP-4551570-A1 NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Dong-A ST Co., Ltd. (KR) 2025-05-14 EP disclosed
US-4948887-A FOR UPLAND FIELDS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-08-14 US disclosed
US-4942246-A CARBONYLATION, CONDENSATION, HERBICIDES NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-07-17 US disclosed
CN-1042910-A The allylamine derivatives that replaces, their production method and application thereof BANYU PHARMA CO LTD (JP) 1990-06-13 CN disclosed
EP-0344775-A1 Process for producing 4-benzoyl-5-hydroxypyrazoles NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-12-06 EP disclosed
US-4885022-A Herbicidal pyrazole derivatives NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-12-05 US disclosed
EP-0287951-A2 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-10-26 EP disclosed
CN-88101455-A Pyrazole derivatives and herbicides containing the same 1988-09-28 CN disclosed
EP-0282944-A2 Pyrazole derivative and herbicide containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179043-A1 PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF ACHE, CYP4B1, CYP3A4 ALDH1A1 1130/4885HSD17B10 3895/4885CFTR 4171/4885
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof GLS2, FFAR3, SLC10A1 ALDH1A1 530/4885HSD17B10 252/4885CFTR 194/4885
US-20250154124-A1 PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF ACHE, CYP4B1, CYP3A4 ALDH1A1 1130/4885HSD17B10 3895/4885CFTR 4171/4885
US-20250163010-A1 PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF ACHE, CYP4B1, CYP3A4 ALDH1A1 1130/4885HSD17B10 3895/4885CFTR 4171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.