SCHEMBL5433650

SCHEMBL5433650

Cn1cnc(C(=O)O)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
APOBEC3A P31941 4/20 0.41
APOBEC3G Q9HC16 3/20 0.41
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
PABPC1 P11940 1/20 0.37
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
HPGD P15428 2/20 0.36
BCAT2 O15382 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
PKM P14618 2/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
KDM2B Q8NHM5 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
MAPT P10636 1/20 0.33
ADORA2A P29274 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13688644 0.83 ALDH1A1 (0.42) LMNAALDH1A1APOBEC3AAPOBEC3GKMT2A
SCHEMBL2112227 0.83 ALDH1A1 (0.59) LMNAALDH1A1APOBEC3AAPOBEC3GKMT2A
SCHEMBL2234794 0.79 NPSR1 (0.43) LMNAALDH1A1APOBEC3AAPOBEC3GHPGD
SCHEMBL26348723 0.79 ALDH1A1 (0.39) LMNAALDH1A1APOBEC3AAPOBEC3GKMT2A
Methylamine SCHEMBL5149607 0.78 APOBEC3A (0.47) LMNAALDH1A1APOBEC3AAPOBEC3GKMT2A
SCHEMBL5726080 0.77 BCAT2 (0.44) LMNAAPOBEC3AAPOBEC3GKMT2AMEN1
SCHEMBL67836 0.77 APOBEC3A (0.50) LMNAALDH1A1APOBEC3AAPOBEC3GKMT2A
SCHEMBL28226024 0.77 ALDH1A1 (0.39) LMNAALDH1A1KMT2AMEN1PABPC1
SCHEMBL28314802 0.76 CYP2C19 (0.43) LMNAALDH1A1APOBEC3AAPOBEC3GPKM
SCHEMBL13788536 0.75 ALDH1A1 (0.38) LMNAALDH1A1APOBEC3AAPOBEC3GKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120041061-A Antibacterial coating, color steel plate and preparation method thereof 合肥禾盛新型材料有限公司 2025-05-27 CN claimed
CN-120041061-A Antibacterial coating, color steel plate and preparation method thereof 合肥禾盛新型材料有限公司 2025-05-27 CN disclosed
US-20070135454-A1 Bicyclic pyrimidin-4(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1-receptor(vr1) BAYLISS TRACY 2007-06-14 US disclosed
EP-1687306-A1 BICYCLIC PYRIMIDIN-4-(3H)-ONES AND ANALOGUES AND DERIVATIVES THEREOF WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1) MERCK SHARP & DOHME LTD. (GB) 2006-08-09 EP disclosed
WO-2005049613-A1 BICYCLIC PYRIMIDIN-4-(3H)-ONES AND ANALOGUES AND DERIVATIVES THEREOF WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1) MERCK SHARP & DOHME LIMITED (GB) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135454-A1 Bicyclic pyrimidin-4(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1-receptor(vr1) TRPV1, TRPV2, TRPV4 LMNA 4257/4885ALDH1A1 825/4885APOBEC3A 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.