Methylamine

Methylamine

SCHEMBL5149607

CN.CN.Cn1cnc(C(=O)O)c1C(=O)O.Cn1cnc(C(=O)O)c1C(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 4/20 0.47
APOBEC3G Q9HC16 3/20 0.47
PKM P14618 2/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.45
CTDSP1 Q9GZU7 2/20 0.41
MEN1 O00255 1/20 0.39
PABPC1 P11940 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
NPC1 O15118 1/20 0.35
LMNA P02545 2/20 0.35
BCAT2 O15382 1/20 0.35
HPGD P15428 1/20 0.35
KDM2B Q8NHM5 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDR P35968 1/20 0.33
EGLN1 Q9GZT9 1/20 0.32
MYC P01106 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67836 0.96 APOBEC3A (0.50) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL14736244 0.79 APOBEC3A (0.44) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL5433650 0.78 LMNA (0.42) APOBEC3AAPOBEC3GPKMGAATSHR
Methylamine SCHEMBL6091448 0.76 PKM (0.57) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL14736538 0.75 APOBEC3A (0.60) APOBEC3AAPOBEC3GTSHRCTDSP1MEN1
SCHEMBL3054669 0.75 APOBEC3A (0.42) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL5726080 0.75 BCAT2 (0.44) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL21879818 0.75 APOBEC3A (0.42) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL20164040 0.75 PKM (0.47) APOBEC3AAPOBEC3GPKMGAATSHR
SCHEMBL23716719 0.73 APOBEC3A (0.41) APOBEC3AAPOBEC3GPKMGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539707-A4 METHOD AND COMPOUNDS FOR PROMOTING HEALING AND REDUCING INFLAMMATION BIODIEM LTD (AU) 2007-05-30 EP disclosed
US-20060135587-A1 Method and compounds for promoting healing and reducing inflammation BIODIEM, LTD. (AU) 2006-06-22 US disclosed
EP-1539707-A1 METHOD AND COMPOUNDS FOR PROMOTING HEALING AND REDUCING INFLAMMATION Biodiem Ltd. (AU) 2005-06-15 EP disclosed
WO-2004013108-A1 METHOD AND COMPOUNDS FOR PROMOTING HEALING AND REDUCING INFLAMMATION BIODIEM LIMITED (AU) 2004-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135587-A1 Method and compounds for promoting healing and reducing inflammation IL1B, MIF, ALKBH5 APOBEC3A 3574/4885APOBEC3G 3236/4885PKM 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.