SCHEMBL543373

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10083848	0.81	LMNA (0.47)	ALDH1A1KDM4EHSD17B10HPGDLMNA
	SCHEMBL3511612	0.78	LMNA (0.59)	ALDH1A1KDM4EHSD17B10LMNATSHR
	SCHEMBL3125776	0.77	CYP3A4 (0.59)	ALDH1A1KDM4EHSD17B10HPGDLMNA
	SCHEMBL18367781	0.76	LMNA (0.42)	ALDH1A1KDM4EHSD17B10HPGDLMNA
	SCHEMBL7864367	0.76	LMNA (0.43)	ALDH1A1KDM4EHSD17B10HPGDLMNA
	SCHEMBL19726720	0.74	LMNA (0.50)	ALDH1A1KDM4EHSD17B10LMNATSHR
	SCHEMBL19849652	0.73	TSHR (0.53)	ALDH1A1KDM4EHSD17B10LMNATSHR
	SCHEMBL29634134	0.73	TSHR (0.53)	ALDH1A1KDM4EHSD17B10LMNATSHR
	SCHEMBL524457	0.73	LMNA (0.53)	ALDH1A1KDM4EHSD17B10LMNATSHR
	Dimethyl Phthalate SCHEMBL34630	0.72	TSHR (0.74)	ALDH1A1KDM4EHSD17B10LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.