Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941612 | 0.81 | MCL1 (0.50) | MCL1HSD11B1ALDH1A1LMNAMEN1 | |
| SCHEMBL4616939 | 0.80 | HTR6 (0.56) | HSD11B1KDM4EALDH1A1GAASLC40A1 | |
| SCHEMBL5261185 | 0.78 | BCHE (0.47) | MCL1HSD11B1KDM4EALDH1A1GAA | |
| SCHEMBL6916212 | 0.77 | GAA (0.75) | HSD11B1KDM4EALDH1A1GAAPOLB | |
| SCHEMBL7613480 | 0.77 | KDM4E (0.49) | MCL1HSD11B1KDM4EALDH1A1GAA | |
| SCHEMBL19019674 | 0.76 | ALDH1A1 (0.51) | KDM4EALDH1A1GAASLC40A1LMNA | |
| SCHEMBL27858879 | 0.75 | ABCC9 (0.54) | MCL1HSD11B1KDM4EALDH1A1POLB | |
| SCHEMBL8318015 | 0.75 | MCL1 (0.46) | MCL1HSD11B1ALDH1A1POLBLMNA | |
| SCHEMBL30137559 | 0.74 | CA1 (0.55) | KDM4EALDH1A1GAASLC40A1LMNA | |
| SCHEMBL6684584 | 0.74 | CA1 (0.55) | KDM4EALDH1A1GAASLC40A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238763-A1 | Urea derivatives as integrin a4 antagonists | LABORATORIOS ALMIRALL, S.A. | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238763-A1 | Urea derivatives as integrin a4 antagonists | ITGB4, ITGA4, ITGB7 | MCL1 3100/4885HSD11B1 4682/4885KDM4E 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.