SCHEMBL543570

SCHEMBL543570

Cc1ccc(C)n1CCO

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
LMNA P02545 2/20 0.60
MAPT P10636 7/20 0.45
HSD17B10 Q99714 1/20 0.44
PRKCI P41743 1/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 6/20 0.38
MEN1 O00255 3/20 0.38
THRB P10828 2/20 0.38
GAA P10253 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
NR4A1 P22736 1/20 0.38
APEX1 P27695 1/20 0.38
APOBEC3A P31941 1/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4487085 0.84 MAPT (0.63) ALDH1A1LMNAMAPTHSD17B10PRKCI
SCHEMBL9772348 0.82 PRKCI (0.45) ALDH1A1LMNAMAPTPRKCIKMT2A
SCHEMBL31287328 0.79 ALDH1A1 (0.41) ALDH1A1LMNAMAPTHSD17B10KMT2A
SCHEMBL10841779 0.75 HSD17B10 (0.43) ALDH1A1LMNAMAPTHSD17B10KMT2A
SCHEMBL10812558 0.75 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHSD17B10KMT2A
SCHEMBL11489950 0.74 ALDH1A1 (0.43) ALDH1A1LMNAMAPTHSD17B10PRKCI
SCHEMBL11339139 0.74 PRKCI (0.50) ALDH1A1LMNAMAPTPRKCIKMT2A
SCHEMBL7279320 0.72 PRKCI (0.39) ALDH1A1LMNAMAPTPRKCIKMT2A
SCHEMBL9877153 0.72 PRKCI (0.39) ALDH1A1LMNAMAPTPRKCIKMT2A
SCHEMBL11489947 0.72 PRKCI (0.39) ALDH1A1LMNAMAPTPRKCIKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587511-A1 BIO-NANOCOMPOSITE MATERIAL Politecnico di Milano (IT) 2025-07-23 EP claimed
WO-2024057271-A1 BIO-NANOCOMPOSITE MATERIAL POLITECNICO DI MILANO (IT) 2024-03-21 WO claimed
EP-3790849-B1 CEMENT-BASED COMPOSITE MATERIALS COMPRISING SP2 HYBRIDIZED CARBON ALLOTROPES MILANO POLITECNICO (IT) 2025-11-26 EP disclosed
EP-4587511-A1 BIO-NANOCOMPOSITE MATERIAL Politecnico di Milano (IT) 2025-07-23 EP disclosed
US-20250059359-A1 NEW REINFORCING ORGANIC FILLERS FOR ELASTOMERIC COMPOUNDS AND TYRES THAT COMPRISE THEM PIRELLI TYRE S.P.A. (IT) 2025-02-20 US disclosed
EP-4452668-A1 NEW REINFORCING ORGANIC FILLERS FOR ELASTOMERIC COMPOUNDS AND TYRES THAT COMPRISE THEM Pirelli Tyre S.p.A. (IT) 2024-10-30 EP disclosed
CN-118591463-A Novel reinforcing organic fillers for elastomeric compounds and tires comprising them 倍耐力轮胎股份公司 2024-09-03 CN disclosed
US-12037742-B2 Process for coating fibers containing polar moieties POLITECNICO DI MILANO (IT) 2024-07-16 US disclosed
WO-2023119175-A1 NEW REINFORCING ORGANIC FILLERS FOR ELASTOMERIC COMPOUNDS AND TYRES THAT COMPRISE THEM PIRELLI TYRE S.P.A. (IT) 2023-06-29 WO disclosed
WO-2023119175-A1 NEW REINFORCING ORGANIC FILLERS FOR ELASTOMERIC COMPOUNDS AND TYRES THAT COMPRISE THEM PIRELLI TYRE S.P.A. (IT) 2023-06-29 WO disclosed
CN-112204081-B Method for coating fibres containing polar moieties 米兰综合工科大学 2023-06-27 CN disclosed
US-20040186099-A1 Novel heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine LOHRAY BRAJ BHUSHAN (IN) 2004-09-23 US disclosed
EP-1368315-A1 METHOD FOR PREPARING AMLODIPINE Hanmi Pharm. Co., Ltd. (KR) 2003-12-10 EP disclosed
US-20030199498-A1 Novel heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine CADILA HEALTHCARE LIMITED 2003-10-23 US disclosed
US-6492523-B2 SUBJECTING A PYRROLE DERIVATIVE, METHYL AMINOCROTONATE AND 2-CHLOROBENZALDEHYDE TO A HANTZSCH REACTION, AND CONVERTING THE PYRROLE RESIDUE OF THE RESULTING PRODUCT TO AN AMINE GROUP BY THE ACTION OF HYDROXYLAMINE HYDROCHLORIDE. HANMI PHARM. CO., LTD. (KR) 2002-12-10 US disclosed
WO-2002072552-A1 METHOD FOR PREPARING AMLODIPINE HANMI PHARM. CO., LTD. (KR) 2002-09-19 WO disclosed
US-20020132834-A1 Method for preparing amlodipine HANMI SCIENCE CO., LTD. (KR) 2002-09-19 US disclosed
US-4833150-A HYPOTENSIVES, ANTIARRHYTHMIA AGENTS NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-05-23 US disclosed
US-4652573-A HYPOTENSIVE AGENTS NELSON RESEARCH & DEVELOPMENT CO. (US) 1987-03-24 US disclosed
EP-0194685-A1 1,4-Dihydropyridines Whitby Research Incorporated (US) 1986-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199498-A1 Novel heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine CYP11B2, CYP11B1, MAPT ALDH1A1 1829/4885LMNA 1550/4885MAPT 3/4885
US-12037742-B2 Process for coating fibers containing polar moieties PCBP1, CAPG, CKAP4 ALDH1A1 3854/4885LMNA 1786/4885MAPT 130/4885
US-20020132834-A1 Method for preparing amlodipine HNMT, HMBS, QDPR ALDH1A1 887/4885LMNA 853/4885MAPT 2297/4885
US-20040186099-A1 Novel heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine CYP11B2, CYP11B1, MAPT ALDH1A1 1829/4885LMNA 1550/4885MAPT 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.