SCHEMBL543748

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3961766	0.90	ALDH1A1 (0.46)	FFAR4KDM4EALDH1A1MAOBMAPT
	SCHEMBL12021889	0.86	FFAR4 (0.38)	FFAR4KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL5042254	0.84	KDM4E (0.40)	FFAR4KDM4EALDH1A1MAOBMAPT
	SCHEMBL543855	0.82	KDM4E (0.41)	FFAR4KDM4EALDH1A1MAOBMAPT
	SCHEMBL10059969	0.82	KDM4E (0.38)	FFAR4KDM4EALDH1A1MAOBMAPT
	SCHEMBL3961427	0.78	KDM4E (0.38)	FFAR4KDM4EALDH1A1MAOBMAPT
	SCHEMBL10401917	0.78	KDM4E (0.43)	FFAR4KDM4EALDH1A1MAOBMAPT
	SCHEMBL10401758	0.78	KDM4E (0.46)	KDM4EALDH1A1MAOBMAPTHPGD
	SCHEMBL544215	0.77	KDM4E (0.38)	FFAR4KDM4EALDH1A1MAPTHPGD
	SCHEMBL10059981	0.76	ADRB2 (0.37)	FFAR4KDM4EALDH1A1MAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.