Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.65 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.58 |
| ▸ | S100A4 | P26447 | 1/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.51 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | CCND1 | P24385 | 2/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.50 |
| ▸ | PRKACA | P17612 | 2/20 | 0.50 |
| ▸ | PRKACG | P22612 | 2/20 | 0.50 |
| ▸ | PRKACB | P22694 | 2/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662574 | 0.89 | S100A4 (0.55) | ADRA1AADRA1BIMPDH2S100A4CAMK2D | |
| SCHEMBL9085566 | 0.85 | CDK4 (0.74) | ADRA1AADRA1BS100A4CAMK2DCCNE2 | |
| SCHEMBL22152200 | 0.84 | IMPDH2 (0.71) | ADRA1AADRA1BIMPDH2CAMK2DCCNE2 | |
| Nortopsentin C SCHEMBL8615865 | 0.82 | ADRA1A (0.62) | ADRA1AADRA1BIMPDH2S100A4CCNB2 | |
| Nortopsentin B SCHEMBL29489896 | 0.82 | ADRA1A (0.62) | ADRA1AADRA1BIMPDH2S100A4CCNB2 | |
| Nortopsentin C SCHEMBL29489919 | 0.82 | ADRA1A (0.62) | ADRA1AADRA1BIMPDH2S100A4CCNB2 | |
| Nortopsentin B SCHEMBL8615899 | 0.82 | ADRA1A (0.62) | ADRA1AADRA1BIMPDH2S100A4CCNB2 | |
| SCHEMBL1202543 | 0.82 | IMPDH2 (0.63) | IMPDH2CAMK2DCCNE2CDK4CCND1 | |
| SCHEMBL25034159 | 0.80 | MEN1 (0.73) | ADRA1AADRA1BIMPDH2CCNB2CDK1 | |
| SCHEMBL17422753 | 0.79 | IMPDH2 (0.75) | ADRA1AADRA1BIMPDH2CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | HSPA5, TTR, TUFM | ADRA1A 3242/4885ADRA1B 3238/4885IMPDH2 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.