Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568075 | 0.85 | TRPM8 (0.48) | TRPM8PARP1PARP2HTR6KDM4C | |
| SCHEMBL4077454 | 0.84 | USP2 (0.47) | FFAR1KDM4CKDM5AKDM5BTSHR | |
| SCHEMBL9568032 | 0.84 | TRPM8 (0.47) | TRPM8PARP1PARP2HTR6KDM4C | |
| SCHEMBL3590904 | 0.77 | FFAR1 (0.52) | FFAR1KDM4CKDM5AKDM5BTSHR | |
| SCHEMBL30301824 | 0.77 | FFAR1 (0.52) | FFAR1KDM4CKDM5AKDM5BTSHR | |
| SCHEMBL30572310 | 0.76 | BLM (0.50) | PARP1PARP2KDM4CKDM5AKDM5B | |
| SCHEMBL1725811 | 0.76 | BLM (0.50) | PARP1PARP2KDM4CKDM5AKDM5B | |
| SCHEMBL9567999 | 0.75 | TRPM8 (0.47) | TRPM8PARP1PARP2HTR6KDM4C | |
| SCHEMBL5623941 | 0.75 | HTR6 (0.51) | PARP1PARP2HTR6KDM4CKDM5A | |
| Oxalic Acid SCHEMBL5361082 | 0.75 | HTR6 (0.56) | HTR6KDM4CKDM5AKDM5BBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064272-A1 | BENZHYDRYL AMIDE DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS OR INVERSE AGONISTS | ASTRAZENECA AB (SE) | 2007-06-07 | — | — | WO | disclosed |