Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568075 | 0.89 | TRPM8 (0.48) | TRPM8HTR6PARP1PARP2MTNR1B | |
| SCHEMBL5444606 | 0.84 | TRPM8 (0.45) | TRPM8HTR6PARP1PARP2KDM4C | |
| SCHEMBL9049782 | 0.81 | PTGIR (0.38) | TRPM8HTR6PARP1PARP2KDM4C | |
| SCHEMBL9567950 | 0.79 | TRPM8 (0.48) | TRPM8MTNR1BBLM | |
| SCHEMBL9049785 | 0.79 | PTGIR (0.44) | KDM4C | |
| SCHEMBL9567976 | 0.75 | TRPM8 (0.47) | TRPM8HTR6PARP1PARP2KDM4C | |
| SCHEMBL9567955 | 0.75 | CNR1 (0.48) | MTNR1BKDM4CKDM5AKDM5BPDPK1 | |
| SCHEMBL9568037 | 0.73 | CNR1 (0.46) | MTNR1BKDM4CKDM5AKDM5BPDPK1 | |
| SCHEMBL30572310 | 0.73 | BLM (0.50) | PARP1PARP2KDM4CKDM5AKDM5B | |
| SCHEMBL1725811 | 0.73 | BLM (0.50) | PARP1PARP2KDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |