Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214597 | 0.91 | L3MBTL1 (0.44) | L3MBTL1HTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL27044021 | 0.83 | ALDH1A1 (0.47) | L3MBTL1POLBALDH1A1CYP3A4CYP19A1 | |
| SCHEMBL30710100 | 0.83 | ALDH1A1 (0.47) | L3MBTL1POLBALDH1A1CYP3A4CYP19A1 | |
| SCHEMBL5442760 | 0.81 | LMNA (0.47) | L3MBTL1HTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL5441574 | 0.81 | HTR2A (0.52) | L3MBTL1HTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL26694532 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP19A1LMNAESPL1 | |
| SCHEMBL5782401 | 0.78 | ESR1 (0.40) | L3MBTL1NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL29310334 | 0.77 | L3MBTL1 (0.49) | L3MBTL1HTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL29310313 | 0.76 | LMNA (0.45) | L3MBTL1HTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL29310311 | 0.76 | HTR2A (0.47) | L3MBTL1HTR2AHTR2CHTR2BSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043026-A1 | Dopamine receptor modulators as antipsychotic agents | GLAXO GROUP LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
| US-20050222124-A1 | Benzenesulfonamide derivatives as antipsychotic agents | GLAXO GROUP LIMITED (GB) | 2005-10-06 | — | — | US | disclosed |
| EP-1503989-A1 | DOPAMINE RECEPTOR MODULATORS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-09 | — | — | EP | disclosed |
| EP-1474399-A1 | BENZENESULFONAMIDE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003095428-A1 | DOPAMINE RECEPTOR MODULATORS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003068752-A1 | BENZENESULFONAMIDE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043026-A1 | Dopamine receptor modulators as antipsychotic agents | SIGMAR1, CHRM1, OPRM1 | L3MBTL1 1163/4885HTR2A 84/4885HTR2C 30/4885 |
| US-20050222124-A1 | Benzenesulfonamide derivatives as antipsychotic agents | SIGMAR1, CNR1, CBR1 | L3MBTL1 659/4885HTR2A 95/4885HTR2C 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.