Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868380 | 0.88 | ATM (0.43) | ATMDRD2SLC6A4GSK3BPRKCA | |
| SCHEMBL5864364 | 0.88 | ATM (0.43) | ATMDRD2SLC6A4GSK3BPRKCA | |
| SCHEMBL5868247 | 0.88 | ATM (0.43) | ATMDRD2SLC6A4GSK3BPRKCA | |
| SCHEMBL5868298 | 0.85 | ATM (0.40) | ATMDRD2SLC6A4GSK3BPRKCA | |
| Flosequinan SCHEMBL5441172 | 0.85 | ATM (0.47) | ATMDRD2SLC6A4GSK3BPRKCA | |
| Flosequinan SCHEMBL122877 | 0.85 | ATM (0.47) | ATMDRD2SLC6A4GSK3BPRKCA | |
| Flosequinan SCHEMBL5442796 | 0.85 | ATM (0.47) | ATMDRD2SLC6A4GSK3BPRKCA | |
| Flosequinan SCHEMBL6535622 | 0.83 | ATM (0.46) | ATMDRD2SLC6A4GSK3BPRKCA | |
| SCHEMBL5438058 | 0.81 | ATM (0.43) | ATMDRD2SLC6A4GSK3BPRKCA | |
| SCHEMBL5864473 | 0.80 | ATM (0.43) | ATMDRD2SLC6A4GSK3BPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010552-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2007-01-11 | — | — | US | claimed |
| US-20050032833-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC (US) | 2005-02-10 | — | — | US | claimed |
| US-6767914-B2 | REACTING 7-FLUORO-3-FLUOROMETHYLTHIO-1-METHYL-4-QUINOLONE AND M-CHLOROPERBENZOIC ACID TO PRODUCE 7-FLUORO-3-FLUOROMETHYLSULFINYL-1-METHYL-4-QUINOLONE | R.T. ALAMO VENTURES I, LLC | 2004-07-27 | — | — | US | claimed |
| US-20030166679-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2003-09-04 | — | — | US | claimed |
| US-20070010552-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2007-01-11 | — | — | US | disclosed |
| US-20070010552-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2007-01-11 | — | — | US | disclosed |
| US-20070010552-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2007-01-11 | — | — | US | disclosed |
| US-7041677-B2 | Use of monochloroflosequinan in the treatment of sexual dysfunction | R.T. ALAMO VENTURES I, LLC (US) | 2006-05-09 | — | — | US | disclosed |
| US-7034040-B2 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I (US) | 2006-04-25 | — | — | US | disclosed |
| US-20050032833-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC (US) | 2005-02-10 | — | — | US | disclosed |
| US-6767914-B2 | REACTING 7-FLUORO-3-FLUOROMETHYLTHIO-1-METHYL-4-QUINOLONE AND M-CHLOROPERBENZOIC ACID TO PRODUCE 7-FLUORO-3-FLUOROMETHYLSULFINYL-1-METHYL-4-QUINOLONE | R.T. ALAMO VENTURES I, LLC | 2004-07-27 | — | — | US | disclosed |
| US-20030191152-A1 | Use of halogenated heterocyclic compounds in the treatment of sexual dysfunction and cardiovascular disease | R.T. ALAMO VENTURES I, LLC | 2003-10-09 | — | — | US | disclosed |
| US-20030166679-A1 | Fluorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191152-A1 | Use of halogenated heterocyclic compounds in the treatment of sexual dysfunction and cardiovascular disease | SHBG, CYP19A1, FLOT1 | ATM 2698/4885DRD2 27/4885SLC6A4 397/4885 |
| US-20030166679-A1 | Fluorinated heterocyclic compounds and methods of synthesis | FDPS, PFAS, AFF4 | ATM 3766/4885DRD2 1750/4885SLC6A4 2417/4885 |
| US-20050032833-A1 | Fluorinated heterocyclic compounds and methods of synthesis | FDPS, PFAS, AFF4 | ATM 3766/4885DRD2 1750/4885SLC6A4 2417/4885 |
| US-20070010552-A1 | Fluorinated heterocyclic compounds and methods of synthesis | FDPS, PFAS, AFF4 | ATM 3766/4885DRD2 1750/4885SLC6A4 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.