Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174283 | 0.83 | CA2 (0.53) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL31174277 | 0.83 | CA2 (0.53) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL11651990 | 0.82 | TSHR (0.50) | CA2HSD17B10TSHRCYP3A4CA1 | |
| SCHEMBL9773533 | 0.81 | CA2 (0.61) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL71042 | 0.81 | HSD17B10 (0.63) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL507053 | 0.79 | CA2 (0.59) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL31256667 | 0.79 | CA2 (0.59) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL1693883 | 0.79 | CA2 (0.59) | CA2HSD17B10TSHRCYP1A2CYP3A4 | |
| SCHEMBL10128 | 0.78 | IDO1 (0.58) | IGF1RALOX15CYP4F2CYP4A11 | |
| SCHEMBL29413271 | 0.78 | IDO1 (0.58) | IGF1RALOX15CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539078-B | Active small molecular probe for specifically sorting monoamine oxidase, preparation method and application thereof | 南京工业大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114539078-A | Active small molecular probe for specifically sorting monoamine oxidase, preparation method and application thereof | 南京工业大学 | 2022-05-27 | — | — | CN | claimed |
| US-11834421-B2 | Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2023-12-05 | — | — | US | disclosed |
| US-11834421-B2 | Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2023-12-05 | — | — | US | disclosed |
| CN-114544571-B | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-114539078-B | Active small molecular probe for specifically sorting monoamine oxidase, preparation method and application thereof | 南京工业大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-114544571-A | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539078-A | Active small molecular probe for specifically sorting monoamine oxidase, preparation method and application thereof | 南京工业大学 | 2022-05-27 | — | — | CN | disclosed |
| US-8476455-B2 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2013-07-02 | — | — | US | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2007-05-17 | — | — | US | disclosed |
| EP-1694650-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058842-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2005-06-30 | — | — | WO | disclosed |
| EP-1544195-A1 | 1-N-phenyl-amino- 1H-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834421-B2 | Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof | RORC, RORB, RORA | CA2 422/4885HSD17B10 155/4885TSHR 1026/4885 |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | H1-0, H1-5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CA2 2378/4885HSD17B10 4450/4885TSHR 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.