SCHEMBL544596

SCHEMBL544596

CCCCCC(CCC[Si](OCC)(OCC)OCC)CCSSCCC(CCCCC)CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30744930 0.82 OPRM1 (0.40) LMNAOPRM1
SCHEMBL12199856 0.80 LMNA (0.43) LMNAOPRM1
SCHEMBL17123854 0.78 PRKD3 (0.36) LMNA
SCHEMBL28987877 0.77 LMNA (0.36) LMNAOPRM1
SCHEMBL28387932 0.77 ALDH1A1 (0.36) LMNA
Hydrochloric Acid SCHEMBL31373200 0.76 DNM1 (0.40) LMNA
Hydrochloric Acid SCHEMBL10448112 0.76 DNM1 (0.40) LMNA
Hydrochloric Acid SCHEMBL31373199 0.76 DNM1 (0.40) LMNA
SCHEMBL7059549 0.76 USP2 (0.33)
SCHEMBL544597 0.76 OPRM1 (0.33) LMNAOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11066539-B2 Rubber composition KAO CORPORATION (JP) 2021-07-20 US disclosed
US-10717852-B2 Additive for resins KAO CORPORATION (JP) 2020-07-21 US disclosed
US-20200048438-A1 RUBBER COMPOSITION KAO CORPORATION (JP) 2020-02-13 US disclosed
EP-3299412-B1 ADDITIVE FOR RESINS KAO CORP (JP) 2019-07-31 EP disclosed
US-20180142088-A1 ADDITIVE FOR RESINS KAO CORPORATION (JP) 2018-05-24 US disclosed
EP-3299412-A1 ADDITIVE FOR RESINS Kao Corporation (JP) 2018-03-28 EP disclosed
EP-2226354-B1 Rubber composition BRIDGESTONE CORP (JP) 2012-12-12 EP disclosed
US-8110625-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2012-02-07 US disclosed
EP-2223958-B1 Rubber composition BRIDGESTONE CORP (JP) 2011-12-28 EP disclosed
US-20100298488-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2010-11-25 US disclosed
US-7799856-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2010-09-21 US disclosed
EP-2226354-A1 Rubber composition Bridgestone Corporation (JP) 2010-09-08 EP disclosed
EP-2223958-A1 Rubber composition Bridgestone Corporation (JP) 2010-09-01 EP disclosed
US-20040249032-A1 Rubber composition BRIDGESTONE CORPORATION (JP) 2004-12-09 US disclosed
EP-1435375-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2004-07-07 EP disclosed
EP-1081187-B1 Rubber composition containing silica or silicate and salt of an amine BRIDGESTONE CORP (JP) 2004-02-18 EP disclosed
US-6355710-B1 MIXTURE WITH FILLER AND AMINE SALT BRIDGESTONE CORPORATION (JP) 2002-03-12 US disclosed
EP-1081187-A2 Rubber composition containing silica or silicate and salt of an amine BRIDGESTONE CORPORATION (JP) 2001-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298488-A1 RUBBER COMPOSITION RAD50, RAD54L, VCL LMNA 377/4885OPRM1 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.