Methoxymethane

Methoxymethane

SCHEMBL17812950

C=C(C(=O)OCCO)C(C=CC#N)C=Cc1ccccc1.COC

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
POLB P06746 2/20 0.32
CTSC P53634 1/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
CYP1A2 P05177 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
CASP1 P29466 1/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CTSL P07711 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL533420 0.97 AKR1B10 (0.35) ALDH1A1AKR1B10AKR1B1LMNACYP3A4
SCHEMBL437822 0.90 AKR1B10 (0.36) ALDH1A1AKR1B10AKR1B1LMNACYP3A4
SCHEMBL544657 0.85 TDP1 (0.38) ALDH1A1LMNACYP3A4CTSCCYP1A2
Butadiene SCHEMBL11122770 0.82 TDP1 (0.36) ALDH1A1LMNACYP3A4CTSCMEN1
SCHEMBL10932584 0.79 LMNA (0.38) ALDH1A1LMNACYP3A4POLBKMT2A
SCHEMBL3630361 0.79 MGLL (0.47) ALDH1A1
SCHEMBL1425048 0.78 CYP1A2 (0.41) ALDH1A1LMNACYP3A4CYP1A2TDP1
Butadiene SCHEMBL5050055 0.78 TSHR (0.40) ALDH1A1AKR1B10AKR1B1LMNACYP3A4
SCHEMBL441192 0.75 POLB (0.38) ALDH1A1AKR1B10AKR1B1LMNACYP3A4
SCHEMBL1533140 0.74 LMNA (0.41) ALDH1A1AKR1B10AKR1B1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9366962-B1 Negative-working lithographic printing plate precursor and use EASTMAN KODAK COMPANY (US) 2016-06-14 US disclosed