SCHEMBL5448243

SCHEMBL5448243

CCCc1[c]c(CCN)cc(C)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
TAAR1 Q96RJ0 4/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
HTR2A P28223 1/20 0.31
HTR1D P28221 1/20 0.31
HRH1 P35367 1/20 0.31
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1780256 0.89 NOS2 (0.39) NOS2NOS3NOS1
SCHEMBL27692561 0.78 NOS3 (0.35) NOS2NOS3NOS1
SCHEMBL1777232 0.76 NOS2 (0.42) NOS2NOS3NOS1
SCHEMBL27408797 0.74 CSNK2A1 (0.31)
SCHEMBL1776980 0.72 PTGS2 (0.41) NOS2HTR2A
SCHEMBL6683472 0.72 PTGS2 (0.41) NOS2HTR2A
SCHEMBL9478817 0.71 NOS2 (0.39) NOS2
SCHEMBL147801 0.70 CNR1 (0.37)
SCHEMBL263267 0.69 NOS3 (0.34) NOS2NOS3
SCHEMBL23742694 0.68 TAAR1 (0.50) NOS2NOS3NOS1TAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8796193-B2 Refrigerating machine oil compositions NIPPON OIL CORPORATION (JP) 2014-08-05 US disclosed
US-20070155635-A1 Refrigerating machine oil compositions NIPPON OIL CORPORATION (JP) 2007-07-05 US disclosed