Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693996 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL23694526 | 0.81 | CYP2D6 (0.40) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL5712077 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL29532002 | 0.81 | DRD2 (0.60) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL18030756 | 0.81 | DRD2 (0.60) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL22210696 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL20329971 | 0.79 | HTR7 (0.61) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL18612248 | 0.79 | HTR7 (0.61) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL13910341 | 0.79 | HTR7 (0.61) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 | |
| SCHEMBL29531994 | 0.79 | HTR7 (0.61) | ALDH1A1CYP2D6CYP2C19CYP1A2ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7276606-B2 | Phenantridine analogues and uses thereof | 4SC AG (DE) | 2007-10-02 | — | — | US | disclosed |
| EP-1652841-A1 | Novel phenantridine analogues and their use as inhibitors of hyperproliferation of T cells and/or keratinocytes | Switch Biotech Aktiengesellschaft (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20050282801-A1 | Novel phenantridine analogues and uses thereof | SWITCH BIOTECH AG (DE) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282801-A1 | Novel phenantridine analogues and uses thereof | P2RX4, P2RX5, CLIC4 | ALDH1A1 2566/4885CYP2D6 609/4885CYP2C19 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.