Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570209 | 0.98 | CYP2C19 (0.56) | BLMPOLBATMCYP2C19ACHE | |
| Bromide SCHEMBL28898530 | 0.96 | CYP2C19 (0.54) | BLMPOLBATMCYP2C19ACHE | |
| Iodide SCHEMBL608288 | 0.96 | CYP2C19 (0.54) | BLMPOLBATMCYP2C19ACHE | |
| SCHEMBL16353013 | 0.88 | CYP2C19 (0.54) | BLMPOLBATMCYP2C19ACHE | |
| SCHEMBL5335351 | 0.87 | CYP2C19 (0.62) | BLMPOLBATMCYP2C19ACHE | |
| SCHEMBL16353066 | 0.85 | CYP2C19 (0.60) | BLMPOLBATMCYP2C19ACHE | |
| SCHEMBL16353072 | 0.85 | CYP2C19 (0.60) | BLMPOLBATMCYP2C19ACHE | |
| Hydrochloric Acid SCHEMBL28454759 | 0.83 | BLM (0.61) | BLMPOLBATMCYP2C19ACHE | |
| SCHEMBL16353033 | 0.81 | DNM1 (0.39) | BLMPOLBATMCYP2C19ACHE | |
| SCHEMBL1057055 | 0.80 | CYP2C19 (0.60) | BLMPOLBATMCYP2C19ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384937-A | Efficient yeast display carrier and yeast display method | 百奥泰生物制药股份有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-115165786-B | Equivalent clear sky radiation correction method for infrared hyperspectral atmospheric detector based on imager | 国家卫星气象中心(国家空间天气监测预警中心) | 2023-09-19 | — | — | CN | claimed |
| CN-115165786-A | Equivalent clear sky radiation correction method for infrared hyperspectral atmosphere detector based on imager | 国家卫星气象中心(国家空间天气监测预警中心) | 2022-10-11 | — | — | CN | claimed |
| CN-115101675-A | Perovskite-based efficient full-glass assembly | 保定嘉盛光电科技股份有限公司 | 2022-09-23 | — | — | CN | claimed |
| US-12323171-B2 | Radio frequency module and communication device | MURATA MANUFACTURING CO. , LTD. (JP) | 2025-06-03 | — | — | US | disclosed |
| WO-2025071519-A1 | A FORMULATION FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE | T.C. USKUDAR UNIVERSITESI (TR) | 2025-04-03 | — | — | WO | disclosed |
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | UNIVERSITY OF WASHINGTON | 2025-04-03 | — | — | US | disclosed |
| CN-109386408-B | System and method for a split exhaust engine system | 福特全球技术公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024255827-A1 | USE OF HETEROCYCLIC ANTI-TUMOR COMPOUND | 石药集团中奇制药技术（石家庄）有限公司 | 2024-12-19 | — | — | WO | disclosed |
| CN-119139313-A | Application of heterocyclic antitumor compound | 石药集团中奇制药技术（石家庄）有限公司 | 2024-12-17 | — | — | CN | disclosed |
| US-12121555-B1 | Method for inhibiting enzyme activity using Boscia senegalensis | King Faisal University (SA) | 2024-10-22 | — | — | US | disclosed |
| EP-3639817-B1 | COMPOSITIONS CONTAINING PTEROSIN COMPOUND AND DERIVATIVES THEREOF ACTIVE INGREDIENTS FOR PREVENTION OR TREATMENT OF DEGENERATIVE BRAIN DISEASES | KORPHARM CO LTD (KR) | 2024-10-09 | — | — | EP | disclosed |
| US-5547977-A | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8(and 1,3A,8)-di (and Tri) methylpyrrolo (2,3-B) indoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| US-5541340-A | Method of preparing 1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-Di(and Tri)methylpyrrolo[2,3,-b] indoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541216-A | Memory enhancing and analgsic 1,2,3,3A,8,8A-Hexahydro--3A, 8(And1,3A,8)-Di (and Tri) Methylpyrrolo(2,3-B Indoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0253372-B1 | 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5272061-A | Assay for serum cholinesterase activity | EASTMAN KODAK COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0533283-A1 | Assay for serum cholinesterase acitivity | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-03-24 | — | — | EP | disclosed |
| US-4791107-A | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0253372-A2 | 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | DHFR, CCNH, ODC1 | ACHE 3527/4885BLM 96/4885POLB 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.