Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570209 | 0.98 | CYP2C19 (0.56) | CYP2C19POLBBLMATMACHE | |
| Hydrochloric Acid SCHEMBL5450062 | 0.96 | BLM (0.57) | CYP2C19POLBBLMATMACHE | |
| Bromide SCHEMBL28898530 | 0.96 | CYP2C19 (0.54) | CYP2C19POLBBLMATMACHE | |
| SCHEMBL16353013 | 0.88 | CYP2C19 (0.54) | CYP2C19POLBBLMATMACHE | |
| SCHEMBL5335351 | 0.87 | CYP2C19 (0.62) | CYP2C19POLBBLMATMACHE | |
| SCHEMBL16353072 | 0.85 | CYP2C19 (0.60) | CYP2C19POLBBLMATMACHE | |
| SCHEMBL16353066 | 0.85 | CYP2C19 (0.60) | CYP2C19POLBBLMATMACHE | |
| Iodide SCHEMBL5144335 | 0.83 | CYP2C19 (0.58) | CYP2C19POLBBLMATMACHE | |
| SCHEMBL16353033 | 0.81 | DNM1 (0.39) | CYP2C19POLBBLMATMACHE | |
| SCHEMBL1057055 | 0.80 | CYP2C19 (0.60) | CYP2C19POLBBLMATMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060839-A | Vegetable pesticide residue rapid screening and detecting method | 云浮市云安区农业发展服务中心 | 2026-05-19 | — | — | CN | claimed |
| CN-119372283-B | Cholinesterase determination reagent and application thereof | 中生北控生物科技股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119372283-A | Cholinesterase determination reagent and application thereof | 中生北控生物科技股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-115722210-B | Recursive nanofiber-based detection material and preparation method and application thereof | 广西大学 | 2024-02-20 | — | — | CN | claimed |
| CN-108586300-B | Synthetic method of S-butyrylthiocholine iodide | 成都福柯斯医药技术有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-106680222-B | Cholinesterase measures reagent and kit | 郑州科欣生物技术有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-108586300-A | A kind of synthetic method of S- butyrylthiocholine iodides | 成都福柯斯医药技术有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-106680222-A | Reagent for determining cholinesterase and kit | 郑州科欣生物技术有限公司 | 2017-05-17 | — | — | CN | claimed |
| EP-2035032-A2 | METHODS FOR ESTER DETOXICATION | Human Biomolecular Research Institute (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2007146003-A2 | METHODS FOR ESTER DETOXICATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2007-12-21 | — | — | WO | claimed |
| US-20070286846-A1 | Novel methods for ester detoxication | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2007-12-13 | — | — | US | claimed |
| US-6773822-B2 | ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. | TEMPLE-INLAND FOREST PRODUCTS CORPORATION | 2004-08-10 | — | — | US | claimed |
| EP-0533283-B1 | Assay for serum cholinesterase acitivity | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-12-11 | — | — | EP | claimed |
| US-5272061-A | Assay for serum cholinesterase activity | EASTMAN KODAK COMPANY (US) | 1993-12-21 | — | — | US | claimed |
| EP-0533283-A1 | Assay for serum cholinesterase acitivity | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-03-24 | — | — | EP | claimed |
| CN-122060839-A | Vegetable pesticide residue rapid screening and detecting method | 云浮市云安区农业发展服务中心 | 2026-05-19 | — | — | CN | disclosed |
| EP-4153561-B1 | 9H-FLUOREN DERIVATES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | UNIV JAGIELLONSKI (PL) | 2026-04-29 | — | — | EP | disclosed |
| EP-0088636-A2 | Quantitative analysis apparatus and method | BIO-METRICS SYSTEMS, INC. (US) | 1983-09-14 | — | — | EP | disclosed |
| EP-0083582-A1 | IMMOBILIZED CHOLINESTERASE ENZYME PREPARATIONS AND A PROCESS FOR THE PREPARATION THEREOF. | REANAL FINOMVEGYSZERGYAR (HU) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000345-A1 | IMMOBILIZED CHOLINESTERASE ENZYME PREPARATIONS AND A PROCESS FOR THE PREPARATION THEREOF | BOROSS, László | 1983-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070286846-A1 | Novel methods for ester detoxication | CES2, BCHE, ACHE | ACHE 3/4885CYP2C19 306/4885POLB 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.