Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596333 | 0.85 | LMNA (0.57) | HPGDKMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL22610228 | 0.83 | LMNA (0.58) | HPGDKMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL16596330 | 0.78 | LMNA (0.56) | ALOX12LMNACYP1A2CYP2C19 | |
| SCHEMBL8993787 | 0.77 | SOAT2 (0.64) | ALDH1A1HPGDKMT2AALOX12LMNA | |
| SCHEMBL5446534 | 0.74 | ALDH1A1 (0.66) | ALDH1A1HPGDKMT2AALOX12LMNA | |
| SCHEMBL5449989 | 0.74 | TDP1 (0.71) | ALDH1A1KMT2AALOX12LMNACYP2C19 | |
| Dipyridyl SCHEMBL28452523 | 0.74 | CYP1A2 (0.56) | LMNACYP1A2CYP2C19 | |
| SCHEMBL27686977 | 0.73 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ALMNAMAPT | |
| SCHEMBL13204664 | 0.73 | RAB9A (0.58) | ALDH1A1KMT2ALMNA | |
| SCHEMBL7824959 | 0.72 | HPGD (0.63) | ALDH1A1HPGDKMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |