Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453670 | 0.86 | CYP2D6 (0.49) | ALDH1A1L3MBTL1KDM4ETSHRHSD17B10 | |
| SCHEMBL20460315 | 0.83 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1KMT2ANPC1MEN1 | |
| SCHEMBL5448713 | 0.81 | RAB9A (0.60) | GRM7ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL5449544 | 0.81 | KDM4E (0.46) | ALDH1A1L3MBTL1KDM4ETSHRHSD17B10 | |
| SCHEMBL5451561 | 0.80 | KMT2A (0.46) | ALDH1A1L3MBTL1KDM4ETSHRHSD17B10 | |
| SCHEMBL20460377 | 0.79 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KMT2ANPC1MEN1 | |
| SCHEMBL5458527 | 0.79 | KMT2A (0.48) | ALDH1A1KDM4EKMT2ANPC1MEN1 | |
| SCHEMBL5458119 | 0.78 | MTNR1A (0.50) | KMT2ANPC1MEN1TAAR1DPP8 | |
| SCHEMBL30641865 | 0.78 | DRD2 (0.51) | KDM4EHSD17B10KMT2ANPC1ABHD6 | |
| SCHEMBL5447851 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | GRM7 330/4885ALDH1A1 489/4885L3MBTL1 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.