Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449544 | 0.86 | KDM4E (0.46) | KMT2AMEN1KDM4ETSHRCYP1A2 | |
| SCHEMBL5453670 | 0.81 | CYP2D6 (0.49) | KMT2AMEN1KDM4ETSHRALDH1A1 | |
| SCHEMBL5451032 | 0.80 | GRM7 (0.48) | KMT2AMEN1KDM4ETSHRALDH1A1 | |
| SCHEMBL5458119 | 0.77 | MTNR1A (0.50) | KMT2AMEN1NPC1TAAR1DPP8 | |
| SCHEMBL30641865 | 0.77 | DRD2 (0.51) | KMT2AKDM4EHSD17B10NPC1ALOX15 | |
| SCHEMBL20460315 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL20460387 | 0.74 | DRD2 (0.47) | KMT2AMEN1TSHRALDH1A1HSD17B10 | |
| SCHEMBL14067047 | 0.74 | NOTUM (0.58) | KDM4EHSD17B10NPC1ALOX15ABHD6 | |
| SCHEMBL5452585 | 0.73 | ABHD6 (0.50) | KDM4EHSD17B10NPC1ALOX15ABHD6 | |
| SCHEMBL5456195 | 0.73 | KDM4E (0.60) | KMT2AMEN1KDM4ETSHROXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | KMT2A 2911/4885MEN1 2444/4885KDM4E 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.